Simultaneous determination of monofluorophosphate and fluoride in toothpaste by capillary electrophoresis

Abstract

Monofluorophosphate and fluoride in various brands of toothpaste were determined by capillary electrophoresis (CE) with indirect UV detection. The electrolyte used was 10 mM chromate and 0.1 mM cetyltrimethylammonium bromide (CTAB) solution at pH of 9.37. Analysis was completed within 8 min when the voltage was set at 15 kV(negative polarity). The CE method was compared with a reference method based on ion chromatography (IC). The results obtained by the CE method agreed with those obtained by the IC method. The CE method was found to be superior in terms of speed and simplicity.