Silver-catalysed intramolecular hydroamination of alkynes with trichloroacetimidates

Abstract

Silver(i) complexes catalyse the intramolecular addition of trichloroacetimidates to alkynes. In the absence of a ligand, the selectivity of the reaction is dependent upon the nature of the counter-anion and solvent. The introduction of non-chelating nitrogeneous ligands suppresses competitive Brønsted acid catalysis, improving the yield and selectivity of the reaction. © 2013 The Royal Society of Chemistry.