1. ScholarBank@NUS
  2. 1. Staff
  3. Staff Publications
Please use this identifier to cite or link to this item: https://doi.org/10.1002/anie.201003257
DC FieldValue
dc.titleMicroarray-assisted high-throughput identification of a cell-permeable small-molecule binder of 14-3-3 proteins
dc.contributor.authorWu, H.
dc.contributor.authorGe, J.
dc.contributor.authorYao, S.Q.
dc.date.accessioned2014-06-23T05:43:24Z
dc.date.available2014-06-23T05:43:24Z
dc.date.issued2010-09-03
dc.identifier.citationWu, H., Ge, J., Yao, S.Q. (2010-09-03). Microarray-assisted high-throughput identification of a cell-permeable small-molecule binder of 14-3-3 proteins. Angewandte Chemie - International Edition 49 (37) : 6528-6532. ScholarBank@NUS Repository. https://doi.org/10.1002/anie.201003257
dc.identifier.issn14337851
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/76488
dc.description.abstractThe way to a 14-3-3 binder: A fragment-based combinatorial small-molecule microarray generates affinity-based fingerprints of the 14-3-3σ protein. One small molecule (see picture; in red box) that disrupts the 14-3-3/protein interaction (green/blue) has been identified. The compound is cell-permeable and possesses both in vitro and in-cell activities.© 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/anie.201003257
dc.sourceScopus
dc.subjectCombinatorial chemistry
dc.subjectFragment-based screening
dc.subjectMicroarrays
dc.subjectProtein-protein interactions
dc.subjectProteins
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1002/anie.201003257
dc.description.sourcetitleAngewandte Chemie - International Edition
dc.description.volume49
dc.description.issue37
dc.description.page6528-6532
dc.description.codenACIEA
dc.identifier.isiut000282477500008
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.