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Title: Determination of antihistamines in pharmaceuticals by capillary electrophoresis
Authors: Ong, C.P. 
Ng, C.L.
Lee, H.K. 
Li, S.F.Y. 
Issue Date: 27-Dec-1991
Citation: Ong, C.P.,Ng, C.L.,Lee, H.K.,Li, S.F.Y. (1991-12-27). Determination of antihistamines in pharmaceuticals by capillary electrophoresis. Journal of Chromatography A 588 (1-2) : 335-339. ScholarBank@NUS Repository.
Abstract: Capillary electrophoresis with on-column UV detection at 214 nm was used to separate a group of nine antihistamines. All these compounds were satisfactorily separated within ca. 6 min using a mixed carrier system containing sodium dodecyl sulphate with β-cyclodextrin and tetrabutylammonium hydrogensulphate as modifiers. The application of the method to the determination of the amount of antihistamines present in commercial pharmaceutical samples was demonstrated. In addition, the migration behaviour of the antihistamines in the mixed carrier system was examined. © 1991.
Source Title: Journal of Chromatography A
ISSN: 00219673
Appears in Collections:Staff Publications

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