Please use this identifier to cite or link to this item: https://doi.org/10.1039/c2sc20219k
DC FieldValue
dc.titleChiral crystallization of aromatic helical foldamers via complementarities in shape and end functionalities
dc.contributor.authorZhao, H.
dc.contributor.authorOng, W.Q.
dc.contributor.authorZhou, F.
dc.contributor.authorFang, X.
dc.contributor.authorChen, X.
dc.contributor.authorLi, S.F.Y.
dc.contributor.authorSu, H.
dc.contributor.authorCho, N.-J.
dc.contributor.authorZeng, H.
dc.date.accessioned2014-06-23T05:34:11Z
dc.date.available2014-06-23T05:34:11Z
dc.date.issued2012-06
dc.identifier.citationZhao, H., Ong, W.Q., Zhou, F., Fang, X., Chen, X., Li, S.F.Y., Su, H., Cho, N.-J., Zeng, H. (2012-06). Chiral crystallization of aromatic helical foldamers via complementarities in shape and end functionalities. Chemical Science 3 (6) : 2042-2046. ScholarBank@NUS Repository. https://doi.org/10.1039/c2sc20219k
dc.identifier.issn20416520
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/75748
dc.description.abstractBiomolecules such as α-helices are exclusively right-handed without contamination by their left-handed counterparts. Within the abiotic world, chiral or external perturbations have to be applied to the abiotic helical foldamers or polymers to control and bias their helical screw sense. Otherwise, it is not possible to separate racemic helical foldamers composed of achiral building blocks. By designing two complementary "sticky" groups, incorporating them into the ends of helical pentamers and taking advantage of the energetically more favored full overlap, which involves helical backbones, we succeeded in demonstrating, for the first time, a spontaneous resolution of racemic helices into their enantiopure single-handed helical forms via chiral crystallization without the use of chiral auxiliary or external stimuli. © 2012 The Royal Society of Chemistry.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c2sc20219k
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1039/c2sc20219k
dc.description.sourcetitleChemical Science
dc.description.volume3
dc.description.issue6
dc.description.page2042-2046
dc.identifier.isiut000304365000042
Appears in Collections:Staff Publications

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