Please use this identifier to cite or link to this item: https://doi.org/10.3390/molecules18022255
DC FieldValue
dc.titleCharacterization of proanthocyanidins in stems of Polygonum multiflorum thunb as strong starch hydrolase inhibitors
dc.contributor.authorWang, H.
dc.contributor.authorSong, L.
dc.contributor.authorFeng, S.
dc.contributor.authorLiu, Y.
dc.contributor.authorZuo, G.
dc.contributor.authorLai, F.
dc.contributor.authorHe, G.
dc.contributor.authorChen, M.
dc.contributor.authorHuang, D.
dc.date.accessioned2014-06-23T05:33:52Z
dc.date.available2014-06-23T05:33:52Z
dc.date.issued2013-02
dc.identifier.citationWang, H., Song, L., Feng, S., Liu, Y., Zuo, G., Lai, F., He, G., Chen, M., Huang, D. (2013-02). Characterization of proanthocyanidins in stems of Polygonum multiflorum thunb as strong starch hydrolase inhibitors. Molecules 18 (2) : 2255-2265. ScholarBank@NUS Repository. https://doi.org/10.3390/molecules18022255
dc.identifier.issn14203049
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/75723
dc.description.abstractCharacterzation of polyphenolic compounds in the stems of P. multiflorum was conducted using HPLC, high resolution LC-MS and LC-MSn. Proanthocyanidins in particular were isolated in 4.8% yield using solvent extraction followed by Sephadex LH-20 fractionation. HPLC analysis using a diol column revealed oligomers (from dimer to nonamer) as minor components, with (epi)catechin monomeric units predominating, and oligomers with higher degree of polymerization being dominant. Thiolysis treatment of the proanthocyanidins using mercaptoacetic acid produced thioether derivatives of (epi)catechin as the major product and a mean value of the degree of polymerization of 32.6 was estimated from the ratio of terminal and extension units of the (epi)catechin. The isolated proanthocyanidins were shown to strongly inhibit α-amylase with an acarbose equivalence (AE) value of 1,954.7 μmol AE/g and inhibit α-glucosidase with an AE value of 211.1 μmol AE/g. © 2013 by the authors.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.3390/molecules18022255
dc.sourceScopus
dc.subjectα-amylase; (epi)catechin
dc.subjectP. multiflorum
dc.subjectProanthocyanidins
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.3390/molecules18022255
dc.description.sourcetitleMolecules
dc.description.volume18
dc.description.issue2
dc.description.page2255-2265
dc.description.codenMOLEF
dc.identifier.isiut000315400600070
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

19
checked on May 28, 2020

WEB OF SCIENCETM
Citations

15
checked on May 28, 2020

Page view(s)

72
checked on May 31, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.