Please use this identifier to cite or link to this item: https://doi.org/10.1021/cc050088i
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dc.titleA highly efficient solid-phase synthesis of 1,3-substituted xanthines
dc.contributor.authorHe, R.
dc.contributor.authorLam, Y.
dc.date.accessioned2014-06-23T05:30:13Z
dc.date.available2014-06-23T05:30:13Z
dc.date.issued2005-11
dc.identifier.citationHe, R., Lam, Y. (2005-11). A highly efficient solid-phase synthesis of 1,3-substituted xanthines. Journal of Combinatorial Chemistry 7 (6) : 916-920. ScholarBank@NUS Repository. https://doi.org/10.1021/cc050088i
dc.identifier.issn15204766
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/75426
dc.description.abstractA first solid-phase route to 1,3-substituted xanthines has been developed using PS-MB-CHO resin. Cyclocondensation of the polymer-bound aminoimidazole with isocyanates followed by alkylation provided 1,3-substituted xanthines in high yields. Libraries of 12 xanthines and 4 thioxanthines were prepared. © 2005 American Chemical Society.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1021/cc050088i
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.description.doi10.1021/cc050088i
dc.description.sourcetitleJournal of Combinatorial Chemistry
dc.description.volume7
dc.description.issue6
dc.description.page916-920
dc.description.codenJCCHF
dc.identifier.isiut000233352800019
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