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Title: Environmental microbiology-on-a-chip and its future impacts
Authors: Liu, W.-T. 
Zhu, L. 
Issue Date: Apr-2005
Citation: Liu, W.-T., Zhu, L. (2005-04). Environmental microbiology-on-a-chip and its future impacts. Trends in Biotechnology 23 (4) : 174-179. ScholarBank@NUS Repository.
Abstract: Rapid advances in microfabrication, DNA and protein microarray and microfluidic technologies have enabled the development of fully-integrated, miniaturized systems. These so called 'laboratory-on-a-chip' (LOC) devices perform sample preparation (i.e. concentration, separation and purification) together with biochemical reactions and detection steps in a simple and automated manner. We believe LOC technology for environmental microbiology studies will have immediate impacts on microbial monitoring by achieving detection and identification within minutes at the single-cell level, and on microbial ecology by deepening the understanding of microbial community structure and diversity and correlating these with niche-specific functions within a micro space. In the long run, significant impacts are anticipated on environmental metagenomics and proteomics. © 2005 Elsevier Ltd. All rights reserved.
Source Title: Trends in Biotechnology
ISSN: 01677799
DOI: 10.1016/j.tibtech.2005.02.004
Appears in Collections:Staff Publications

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