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Title: Potential mechanism for the laser-fluoride effect on enamel demineralization
Authors: Liu, Y.
Hsu, C.-Y.S. 
Teo, C.M.J. 
Teoh, S.H.
Keywords: caries
low energy
mineral loss
Issue Date: Jan-2013
Citation: Liu, Y., Hsu, C.-Y.S., Teo, C.M.J., Teoh, S.H. (2013-01). Potential mechanism for the laser-fluoride effect on enamel demineralization. Journal of Dental Research 92 (1) : 71-75. ScholarBank@NUS Repository.
Abstract: Laser-induced prevention of dental caries has been studied extensively. However, the cariostatic mechanisms of a combined fluoride-laser treatment are not well-understood. Using micro- computed tomography (micro-CT), we quantified the effect of fluoride and/or Er:YAG laser treatment on enamel demineralization. The mean mineral loss (%/V) for each group was 4,870 ± 1,434 (fluoride followed by laser treatment), 6,341 ± 2,204 (laser treatment), 7,669 ± 2,255 (fluoride treatment), and 10,779 ± 2,936 (control). The preventive effect of the laser (p < 0.001) and fluoride (p = 0.010) treatment was statistically significant. Characterized by micro-x-ray diffraction (XRD) analysis, the significant contraction in the a-axis after both laser and combined laser/fluoride treatment was revealed (both p < 0.05). In conclusion, subablative low-energy Er:YAG laser irradiation following fluoride treatment may instantaneously transform enamel hydroxyapatite into fluoridated hydroxyapatite to reduce enamel solubility as a preventive treatment for enamel demineralization. © 2013 International & American Associations for Dental Research.
Source Title: Journal of Dental Research
ISSN: 00220345
DOI: 10.1177/0022034512466412
Appears in Collections:Staff Publications

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