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Please use this identifier to cite or link to this item: https://doi.org/10.1364/OE.16.018764
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dc.titleFocal modulation microscopy
dc.contributor.authorChen, N.
dc.contributor.authorWong, C.-H.
dc.contributor.authorSheppard, C.J.R.
dc.date.accessioned2014-06-17T09:44:00Z
dc.date.available2014-06-17T09:44:00Z
dc.date.issued2008-11-10
dc.identifier.citationChen, N., Wong, C.-H., Sheppard, C.J.R. (2008-11-10). Focal modulation microscopy. Optics Express 16 (23) : 18764-18769. ScholarBank@NUS Repository. https://doi.org/10.1364/OE.16.018764
dc.identifier.issn10944087
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/67065
dc.description.abstractWe report a novel light microscopy method for high resolution molecular imaging of thick biological tissues with one photon excited fluorescence. Effective optical sectioning and diffraction limited spatial resolution are achieved when imaging deep inside a multiple-scattering medium by the use of focal modulation, a technique for suppressing the background fluorescence signal excited by scattered light. Our method has been validated with animal tissue and an imaging depth around 600 microns has been demonstrated. © 2008 Optical Society of America.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1364/OE.16.018764
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOENGINEERING
dc.description.doi10.1364/OE.16.018764
dc.description.sourcetitleOptics Express
dc.description.volume16
dc.description.issue23
dc.description.page18764-18769
dc.identifier.isiut000260866000023
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