Please use this identifier to cite or link to this item:
|Title:||Well-defined nanoassemblies using gold nanoparticles bearing specific number of DNA strands||Authors:||Wei Jie Qin
|Issue Date:||Jan-2008||Citation:||Wei Jie Qin, Yung, L.Y.L. (2008-01). Well-defined nanoassemblies using gold nanoparticles bearing specific number of DNA strands. Bioconjugate Chemistry 19 (1) : 385-390. ScholarBank@NUS Repository.||Abstract:||The accurate assembly of nanoparticles into specially designed structures is important for the application of nanoparticle-based materials. Here we report the fabrication of well-defined nanoparticle assemblies via the grouping of gold nanoparticles bearing a specific number of short DNA per particle. Furthermore, we explored various conditions that affect the grouping. Our results show that direct linkage of two nanoparticle-bound DNA without the use of linker DNA yields 80% grouping, which is the highest of all conditions tested. Longer hybridization times and buffer conditions with higher ionic strength also increase grouping formation. These results provide key knowledge that controls the hybridization of nanoparticle-bound DNA for achieving well-defined nanoassemblies with high yield. © 2008 American Chemical Society.||Source Title:||Bioconjugate Chemistry||URI:||http://scholarbank.nus.edu.sg/handle/10635/64795||ISSN:||10431802|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 11, 2018
WEB OF SCIENCETM
checked on Dec 19, 2018
checked on Apr 12, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.