Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/64716
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dc.titleThe potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes
dc.contributor.authorLiu, L.
dc.contributor.authorYang, J.
dc.contributor.authorXie, J.
dc.contributor.authorLuo, Z.
dc.contributor.authorJiang, J.
dc.contributor.authorYang, Y.Y.
dc.contributor.authorLiu, S.
dc.date.accessioned2014-06-17T07:50:28Z
dc.date.available2014-06-17T07:50:28Z
dc.date.issued2013-05-07
dc.identifier.citationLiu, L., Yang, J., Xie, J., Luo, Z., Jiang, J., Yang, Y.Y., Liu, S. (2013-05-07). The potent antimicrobial properties of cell penetrating peptide-conjugated silver nanoparticles with excellent selectivity for Gram-positive bacteria over erythrocytes. Nanoscale 5 (9) : 3834-3840. ScholarBank@NUS Repository.
dc.identifier.issn20403364
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/64716
dc.description.abstractSilver nanoparticles are of great interest for use as antimicrobial agents. Studies aimed at producing potent nano-silver biocides have focused on manipulation of particle size, shape, composition and surface charge. Here, we report the cell penetrating peptide catalyzed formation of antimicrobial silver nanoparticles in N,N-dimethylformamide. The novel nano-composite demonstrated a distinctly enhanced biocidal effect toward bacteria (Gram-positive Bacillus subtilis, Gram-negative Escherichia coli) and pathogenic yeast (Candida albicans), as compared to triangular and extremely small silver nanoparticles. In addition, a satisfactory biocompatibility was verified by a haemolysis test. Our results provide a paradigm in developing strategies that can maximize the silver nanoparticle application potentials while minimizing the toxic effects. © 2013 The Royal Society of Chemistry.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/c3nr34254a
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMICAL & BIOMOLECULAR ENGINEERING
dc.description.sourcetitleNanoscale
dc.description.volume5
dc.description.issue9
dc.description.page3834-3840
dc.identifier.isiut000317859400036
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