Please use this identifier to cite or link to this item: https://doi.org/10.1063/1.3247895
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dc.titleSelf-assembly of cholesterol DNA at liquid crystal/aqueous interface and its application for DNA detection
dc.contributor.authorLai, S.L.
dc.contributor.authorHartono, D.
dc.contributor.authorYang, K.-L.
dc.date.accessioned2014-06-17T07:48:43Z
dc.date.available2014-06-17T07:48:43Z
dc.date.issued2009
dc.identifier.citationLai, S.L., Hartono, D., Yang, K.-L. (2009). Self-assembly of cholesterol DNA at liquid crystal/aqueous interface and its application for DNA detection. Applied Physics Letters 95 (15) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.3247895
dc.identifier.issn00036951
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/64566
dc.description.abstractIn this letter, we report a strategy of detecting the DNA targets by using a thin layer of self-assembled cholesterol-labeled DNA probes at the liquid crystal (LC)/aqueous interface. When the system is exposed to 51 μg/ml of complementary DNA targets, the optical appearance of LC shows a continuous change from dark to bright under the crossed polars within 15 min. No obvious change can be observed when the system is exposed to one or two base-pair mismatch DNA targets. This system provides a principle for label-free and real-time detection of DNA targets without any fluorescent labeling. © 2009 American Institute of Physics.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1063/1.3247895
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMICAL & BIOMOLECULAR ENGINEERING
dc.description.doi10.1063/1.3247895
dc.description.sourcetitleApplied Physics Letters
dc.description.volume95
dc.description.issue15
dc.description.page-
dc.description.codenAPPLA
dc.identifier.isiut000270915700084
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