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|Title:||pH-Controllable drug release using hydrogel encapsulated mesoporous silica||Authors:||Song, S.-W.
|Issue Date:||2007||Citation:||Song, S.-W., Hidajat, K., Kawi, S. (2007). pH-Controllable drug release using hydrogel encapsulated mesoporous silica. Chemical Communications (42) : 4396-4398. ScholarBank@NUS Repository. https://doi.org/10.1039/b707626f||Abstract:||Amine-functionalized mesoporous SBA-15 silica loaded with bovine serum albumin (BSA) has been successfully encapsulated with a thin layer coating of poly(acrylic acid) PAA, with the entrapped BSA being released from the PAA-encapsulated SBA-15 at the higher pH value of 7.4 rather than at the lower pH value of 1.2. This novel drug delivery system has a potential application in the release of protein drug to the site of higher pH value, such as small intestine or colon. © The Royal Society of Chemistry.||Source Title:||Chemical Communications||URI:||http://scholarbank.nus.edu.sg/handle/10635/64400||ISSN:||13597345||DOI:||10.1039/b707626f|
|Appears in Collections:||Staff Publications|
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