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Title: pH-Controllable drug release using hydrogel encapsulated mesoporous silica
Authors: Song, S.-W.
Hidajat, K. 
Kawi, S. 
Issue Date: 2007
Citation: Song, S.-W., Hidajat, K., Kawi, S. (2007). pH-Controllable drug release using hydrogel encapsulated mesoporous silica. Chemical Communications (42) : 4396-4398. ScholarBank@NUS Repository.
Abstract: Amine-functionalized mesoporous SBA-15 silica loaded with bovine serum albumin (BSA) has been successfully encapsulated with a thin layer coating of poly(acrylic acid) PAA, with the entrapped BSA being released from the PAA-encapsulated SBA-15 at the higher pH value of 7.4 rather than at the lower pH value of 1.2. This novel drug delivery system has a potential application in the release of protein drug to the site of higher pH value, such as small intestine or colon. © The Royal Society of Chemistry.
Source Title: Chemical Communications
ISSN: 13597345
DOI: 10.1039/b707626f
Appears in Collections:Staff Publications

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