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Title: Construction of physics-based atlas and its application in brain deformation analysis
Authors: Roy, A.
Nowinski, W.L. 
Tay, F.E.H. 
Issue Date: 1-Apr-2006
Citation: Roy, A., Nowinski, W.L., Tay, F.E.H. (2006-04-01). Construction of physics-based atlas and its application in brain deformation analysis. Journal of Physics: Conference Series 34 (1) : 752-756. ScholarBank@NUS Repository.
Abstract: Physics-based modeling provides a powerful tool for investigating the biomechanics of soft tissue deformation incorporated with knowledge of mechanical properties using appropriate boundary conditions. We have developed a physics-based atlas model with detailed anatomical information based on Cerefy Brain Atlas. A nonlinear hyper-viscoelastic mechanical property typically suited for neurosurgery simulation has been incorporated. This model accounts well for brain tissue deformation during neurosurgical procedures (strain rate between 0.001s-1 - 1.0s-1). It is able to simulate the deformation for the entire brain and individual sub-cortical structures as well. The limiting stress relaxation for an infinitesimally small loading has also been obtained (shear modulus reaching 194.62 Pa) exhibiting similarity with a hydrocephalic condition. © 2006 IOP Publishing Ltd.
Source Title: Journal of Physics: Conference Series
ISSN: 17426588
DOI: 10.1088/1742-6596/34/1/124
Appears in Collections:Staff Publications

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