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Title: A computational fluid dynamics study of binary adsorption separation in chromatography
Authors: Wu, Y.X.
Yu, H.W.
Ching, C.B. 
Issue Date: Sep-2004
Citation: Wu, Y.X., Yu, H.W., Ching, C.B. (2004-09). A computational fluid dynamics study of binary adsorption separation in chromatography. Chemical Engineering and Technology 27 (9) : 955-961. ScholarBank@NUS Repository.
Abstract: FEMLAB software was applied to incorporate computational fluid dynamics (CFD) into the simulation of the adsorption-separation process in chromatography. Simulations of both linear and nonlinear processes demonstrated that significant dispersion retarded the separation processes, and that a small inlet induced curved solute concentration profiles, resulting in peak tailing of the elution chromatogram. The linear simulation visually confirmed that a small Stanton number might be another factor for peak tailing. For cases with a reasonably small Stanton number, peak tailing became more serious with decreasing Stanton number. Comparisons between the results of the CFD simulation of the nonlinear case, the corresponding conventional 1-D simulation and the experimental result lead to the conclusion that the CFD simulation is useful for a better understanding of the dynamic adsorption and separation process in a chromatographic column. © 2004 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.
Source Title: Chemical Engineering and Technology
ISSN: 09307516
DOI: 10.1002/ceat.200301985
Appears in Collections:Staff Publications

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