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|Title:||A computational fluid dynamics study of binary adsorption separation in chromatography||Authors:||Wu, Y.X.
|Issue Date:||Sep-2004||Citation:||Wu, Y.X., Yu, H.W., Ching, C.B. (2004-09). A computational fluid dynamics study of binary adsorption separation in chromatography. Chemical Engineering and Technology 27 (9) : 955-961. ScholarBank@NUS Repository. https://doi.org/10.1002/ceat.200301985||Abstract:||FEMLAB software was applied to incorporate computational fluid dynamics (CFD) into the simulation of the adsorption-separation process in chromatography. Simulations of both linear and nonlinear processes demonstrated that significant dispersion retarded the separation processes, and that a small inlet induced curved solute concentration profiles, resulting in peak tailing of the elution chromatogram. The linear simulation visually confirmed that a small Stanton number might be another factor for peak tailing. For cases with a reasonably small Stanton number, peak tailing became more serious with decreasing Stanton number. Comparisons between the results of the CFD simulation of the nonlinear case, the corresponding conventional 1-D simulation and the experimental result lead to the conclusion that the CFD simulation is useful for a better understanding of the dynamic adsorption and separation process in a chromatographic column. © 2004 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim.||Source Title:||Chemical Engineering and Technology||URI:||http://scholarbank.nus.edu.sg/handle/10635/54004||ISSN:||09307516||DOI:||10.1002/ceat.200301985|
|Appears in Collections:||Staff Publications|
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