Please use this identifier to cite or link to this item:
https://doi.org/10.3201/eid1610.100516
Title: | Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore | Authors: | Chen, M.I.C. Lee, V.J.M. Barr, I. Lin, C. Goh, R. Lee, C. Singh, B. Tan, J. Lim, W.-Y. Cook, A.R. Ang, B. Chow, A. Tan, B.H. Loh, J. Shaw, R. Chia, K.S. Lin, R.T.P. Leo, Y.S. |
Issue Date: | Oct-2010 | Citation: | Chen, M.I.C., Lee, V.J.M., Barr, I., Lin, C., Goh, R., Lee, C., Singh, B., Tan, J., Lim, W.-Y., Cook, A.R., Ang, B., Chow, A., Tan, B.H., Loh, J., Shaw, R., Chia, K.S., Lin, R.T.P., Leo, Y.S. (2010-10). Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore. Emerging Infectious Diseases 16 (10) : 1554-1561. ScholarBank@NUS Repository. https://doi.org/10.3201/eid1610.100516 | Abstract: | We describe incidence and risk factors for pandemic (H1N1) 2009 virus infection in healthcare personnel during the June-September 2009 epidemic in Singapore. Personnel contributed 3 serologic samples during June-October2009, with seroconversion defined as a ≥4-fold increase in hemagglutination inhibition titers to pandemic (H1N1) 2009.Of 531 participants, 35 showed evidence of seroconversion. Seroconversion rates were highest in nurses (28/290) and lowest in allied health staff (2/116). Significant risk factor son multivariate analysis were being a nurse (adjusted odd sratio [a OR] 4.5, 95% confidence interval [CI] 1.0-19.6) and working in pandemic (H1N1) 2009 isolation wards (aOR4.5, 95% CI 1.3-15.6). Contact with pandemic (H1N1)2009-infected colleagues (a OR 2.5, 95% CI 0.9-6.6) and larger household size (a OR 1.2, 95% CI 1.0-1.4) were of borderline significance. Our study suggests that seroconversion was associated with occupational and nonoccupational risk factors. | Source Title: | Emerging Infectious Diseases | URI: | http://scholarbank.nus.edu.sg/handle/10635/53138 | ISSN: | 10806040 | DOI: | 10.3201/eid1610.100516 |
Appears in Collections: | Staff Publications |
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