A facile strategy toward conjugated polyelectrolyte with oligopeptide as pendants for biological applications

Please use this identifier to cite or link to this item: https://doi.org/10.1021/am400169v

Title:	A facile strategy toward conjugated polyelectrolyte with oligopeptide as pendants for biological applications
Authors:	Liu, J. Feng, G. Geng, J. Liu, B.
Keywords:	cellular imaging click reaction conjugated polyelectrolyte oligopeptide polyfluorene
Issue Date:	12-Jun-2013
Citation:	Liu, J., Feng, G., Geng, J., Liu, B. (2013-06-12). A facile strategy toward conjugated polyelectrolyte with oligopeptide as pendants for biological applications. ACS Applied Materials and Interfaces 5 (11) : 4511-4515. ScholarBank@NUS Repository. https://doi.org/10.1021/am400169v
Abstract:	We report a facile yet efficient strategy to synthesize biofunctionalized conjugated polyelectrolyte using click reaction between an amphiphilic oligopeptide (R10) and organic soluble polyfluorene (PF) as an example. PF-R10 shows the absorption and emission maxima at ∼380 and ∼430 nm in water, respectively. In addition, it exhibits enhanced fluorescence in acidic circumstance as compared to that in neutral environment because of reduced aggregation, which is confirmed by laser light scattering and atomic force microscopy studies. In view of the penetration property of the grafted R10 peptide, PF-R10 shows excellent cell uptake and labeling ability in cellular imaging. © 2013 American Chemical Society.
Source Title:	ACS Applied Materials and Interfaces
URI:	http://scholarbank.nus.edu.sg/handle/10635/51748
ISSN:	19448244
DOI:	10.1021/am400169v
Appears in Collections:	Staff Publications

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