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Title: Creation of nanostructures by interference lithography for modulation of cell behavior
Authors: Zhu, M.
Zhou, L. 
Li, B. 
Dawood, M.K.
Wan, G. 
Lai, C.Q.
Cheng, H.
Leong, K.C.
Rajagopalan, R. 
Too, H.P.
Choi, W.K. 
Issue Date: Jul-2011
Citation: Zhu, M., Zhou, L., Li, B., Dawood, M.K., Wan, G., Lai, C.Q., Cheng, H., Leong, K.C., Rajagopalan, R., Too, H.P., Choi, W.K. (2011-07). Creation of nanostructures by interference lithography for modulation of cell behavior. Nanoscale 3 (7) : 2723-2729. ScholarBank@NUS Repository.
Abstract: Emerging evidence of the striking differences that can be induced in the behavior of biological cells through topographical modulation of physically and chemically patterned nanostructured surfaces provides a great impetus for developing novel cellular-scale and sub-cellular-scale nanopatterned substrates and for employing them for exciting new applications in life and medical sciences and biotechnology. However, the lack of availability of cost-effective, large-surface-area nanofabricated substrates of appropriate dimensions and features has proved to be a major impediment for research in this area. Here, we demonstrate a simple and cost-effective method based on interference lithography to produce spatially precise and wide-surface-coverage silicon- and polymer-based nanostructures to study how cells react to nanoscale structures or surfaces. © 2011 The Royal Society of Chemistry.
Source Title: Nanoscale
ISSN: 20403364
DOI: 10.1039/c1nr00015b
Appears in Collections:Staff Publications

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