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Title: Outcome of surgical closure of doubly committed subarterial ventricular septal defect
Authors: Sim, E.K.W. 
Grignani, R.T.
Wong, M.-L. 
Quek, S.C. 
Wong, J.C.L. 
Yip, W.C.L.
Lee, C.N.
Issue Date: 1999
Citation: Sim, E.K.W., Grignani, R.T., Wong, M.-L., Quek, S.C., Wong, J.C.L., Yip, W.C.L., Lee, C.N. (1999). Outcome of surgical closure of doubly committed subarterial ventricular septal defect. Annals of Thoracic Surgery 67 (3) : 736-738. ScholarBank@NUS Repository.
Abstract: Background. From 1986 to March 1997, 128 patients diagnosed to have doubly committed subarterial ventricular septal defects (VSD) were reviewed. Patients with aortic regurgitation (AR), and aortic valve (AV) deformity or a large left-to-right shunt across the VSD were offered operation. Forty-five patients (27 men, 18 women) agreed to surgical closure of their VSDs. Methods. Thirty-eight patients had VSD closure alone, and 7 had an additional AV repair. Other associated defects corrected at operation were closure of atrial septal defects, closure of other ventricular septal defects, ligation of patent ductus arteriosus, and repair of ruptured sinus Valsalva aneurysm. Results. There was no mortality nor major morbidity associated with operation. In the 26 patients with AR and AV deformity preoperatively, valve repair was performed in 6 patients. The condition of AR improved in 4, and remained unchanged in 22 patients. In the 10 patients with a deformity of the AV and no AR preoperatively, the condition remained unchanged in 5 patients, from whom 1 had valve operation, but progressed in 5 patients postoperatively at a mean follow-up of 6.4 years. In 9 patients with no deformity of the AV and no AR preoperatively, there was no postoperative AR and no progress of valve deformity. Conclusions. Excellent results were obtained with VSD closure and AV repair. Surgical closure of VSD, if performed before the onset of AV deformity, may prevent progressive AR. If AV repair is performed after the onset of AV deformity, progressive AR may not always be prevented.
Source Title: Annals of Thoracic Surgery
ISSN: 00034975
DOI: 10.1016/S0003-4975(98)01256-9
Appears in Collections:Staff Publications

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