Please use this identifier to cite or link to this item: https://doi.org/10.1093/nar/gni147
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dc.titleA post-processing method for optimizing synthesis strategy for oligonucleotide microarrays
dc.contributor.authorNing, K.
dc.contributor.authorChoi, K.P.
dc.contributor.authorLeong, H.W.
dc.contributor.authorZhang, L.
dc.date.accessioned2013-07-23T09:25:32Z
dc.date.available2013-07-23T09:25:32Z
dc.date.issued2005
dc.identifier.citationNing, K., Choi, K.P., Leong, H.W., Zhang, L. (2005). A post-processing method for optimizing synthesis strategy for oligonucleotide microarrays. Nucleic Acids Research 33 (17) : 1-6. ScholarBank@NUS Repository. https://doi.org/10.1093/nar/gni147
dc.identifier.issn03051048
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/43120
dc.description.abstractThe broad applicability of gene expression profiling to genomic analyses has generated huge demand for mass production of microarrays and hence for improving the cost effectiveness of microarray fabrication. We developed a post-processing method for deriving a good synthesis strategy. In this paper, we assessed all the known efficient methods and our post-processing method for reducing the number of synthesis cycles for manufacturing a DNA-chip of a given set of oligos. Our experimental results on both simulated and 52 real datasets show that no single method consistently gives the best synthesis strategy, and post-processing an existing strategy is necessary as it often reduces the number of synthesis cycles further. © The Author 2005. Published by Oxford University Press. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1093/nar/gni147
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCOMPUTER SCIENCE
dc.contributor.departmentMATHEMATICS
dc.description.doi10.1093/nar/gni147
dc.description.sourcetitleNucleic Acids Research
dc.description.volume33
dc.description.issue17
dc.description.page1-6
dc.description.codenNARHA
dc.identifier.isiut000232593700004
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