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https://doi.org/10.1016/0010-7824(92)90159-Q
Title: | Effect of Norplant®-2 rods on liver, lipid and carbohydrate metabolism | Authors: | Singh, K. Viegas, O.A.C. Loke, D. Ratnam, S.S. |
Issue Date: | 1992 | Citation: | Singh, K., Viegas, O.A.C., Loke, D., Ratnam, S.S. (1992). Effect of Norplant®-2 rods on liver, lipid and carbohydrate metabolism. Contraception 45 (5) : 463-472. ScholarBank@NUS Repository. https://doi.org/10.1016/0010-7824(92)90159-Q | Abstract: | The effect of Norplant®-2 rods on liver, lipid and carbohydrate metabolism was evaluated in 100 women using Norplant®-2 rods. Besides a significant increase in serum bilirubin, there was no other obvious evidence to suggest any possible hepatocellular dysfunction with the use of Norplant®-2 rods. As regards lipid metabolism, decreases in total triglycerides, cholesterol and LDL-cholesterol and HDL-cholesterol were initially seen. These parameters returned to their preinsertion mean at the end of five years. As a result, the value of the HDL-cholesterol/total cholesterol - HDL-cholesterol and LDL-cholesterol/HDL-cholesterol ratios remained around their preinsertion value at the end of five years. All this appears to indicate that the use of Norplant®-2 rods is not directly contributory to cardiovascular risk. The use of Norplant®-2 rods was not associated with any significant effect on carbohydrate metabolism. | Source Title: | Contraception | URI: | http://scholarbank.nus.edu.sg/handle/10635/37180 | ISSN: | 00107824 | DOI: | 10.1016/0010-7824(92)90159-Q |
Appears in Collections: | Staff Publications |
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