Please use this identifier to cite or link to this item: https://doi.org/10.1016/0090-6980(85)90207-2
DC FieldValue
dc.titlePlasma levels of 13,14-dihydro-15-keto PGE2after vaginal application of a new PGE2film
dc.contributor.authorPrasad, R.N.V.
dc.contributor.authorRoy, A.C.
dc.contributor.authorKottegoda, S.R.
dc.date.accessioned2013-04-10T03:02:58Z
dc.date.available2013-04-10T03:02:58Z
dc.date.issued1985
dc.identifier.citationPrasad, R.N.V., Roy, A.C., Kottegoda, S.R. (1985). Plasma levels of 13,14-dihydro-15-keto PGE2after vaginal application of a new PGE2film. Prostaglandins 29 (2) : 269-272. ScholarBank@NUS Repository. https://doi.org/10.1016/0090-6980(85)90207-2
dc.identifier.issn00906980
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/37164
dc.description.abstractTo determine the release and absorption profile of prostaglandin E2 from a new vaginal film formulation containing 850 μg PGE2, serial plasma levels of 13,14-dihydro-15-keto PGE2 were measured by radioimmunoassay in pregnant women between 16 and 18 weeks gestation. A control group, using placebo vaginal film was included in the study. There was a somewhat uniform increase in the plasma levels of the PGE2 metabolite, reaching peak levels between 4 and 6 hours after application of the film. The findings suggest that this drug formulation could be used clinically when slow constant release of the prostaglandin is required over a period of hours such as in pre-induction cervical ripening of term pregnancy.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/0090-6980(85)90207-2
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentOBSTETRICS & GYNAECOLOGY
dc.description.doi10.1016/0090-6980(85)90207-2
dc.description.sourcetitleProstaglandins
dc.description.volume29
dc.description.issue2
dc.description.page269-272
dc.description.codenPRGLB
dc.identifier.isiutA1985AAZ9700010
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