Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.contraception.2004.05.011
DC FieldValue
dc.titleEffect of etonogestrel subdermal contraceptive implant (Implanon®) on liver function tests - A randomized comparative study with Norplant® implants
dc.contributor.authorBiswas, A.
dc.contributor.authorViegas, O.A.C.
dc.date.accessioned2013-04-10T02:59:03Z
dc.date.available2013-04-10T02:59:03Z
dc.date.issued2004
dc.identifier.citationBiswas, A., Viegas, O.A.C. (2004). Effect of etonogestrel subdermal contraceptive implant (Implanon®) on liver function tests - A randomized comparative study with Norplant® implants. Contraception 70 (5) : 379-382. ScholarBank@NUS Repository. https://doi.org/10.1016/j.contraception.2004.05.011
dc.identifier.issn00107824
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/36932
dc.description.abstractThe study aimed to assess the possible differences in effects of Implanon® and Norplant® implants on liver function over 2 years of use. This is a 2-year open randomized study of 80 implant (Implanon® and Norplant®) acceptors. Selected parameters of liver function were tested in the serum before implant insertion and at 6, 12 and 24 months after implant insertion. In both the implant groups, the mean total and unconjugated bilirubin and the gamma-glutaryl transferase levels were significantly raised during implant use. For none of the subjects, at any sampling period, did the levels exceed the normal range in our population. There was no significant elevation of any other liver enzymes in either group. It appears that there may be mild hepatocellular dysfunction associated with the use of both Implanon® and Norplant®, which is possibly of no clinical significance to the healthy acceptor. © 2004 Elsevier Inc. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.contraception.2004.05.011
dc.sourceScopus
dc.subjectEtonogestrel
dc.subjectImplanon®
dc.subjectImplants
dc.subjectLiver function
dc.subjectNorplant®
dc.subjectProgestins
dc.typeArticle
dc.contributor.departmentOBSTETRICS & GYNAECOLOGY
dc.description.doi10.1016/j.contraception.2004.05.011
dc.description.sourcetitleContraception
dc.description.volume70
dc.description.issue5
dc.description.page379-382
dc.description.codenCCPTA
dc.identifier.isiut000225320900005
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