A review of stonefish venoms and toxins

Please use this identifier to cite or link to this item: https://doi.org/10.1016/0163-7258(94)90022-1

Title:	A review of stonefish venoms and toxins
Authors:	Gwee, M.C.E. Low, K.S.Y. Gopalakrishnakone, P. Yuen, R. Khoo, H.E.
Keywords:	endothelium-dependent vasorelaxation stonefish (Synanceja) stonustoxin systemic effects venoms
Issue Date:	1994
Citation:	Gwee, M.C.E., Low, K.S.Y., Gopalakrishnakone, P., Yuen, R., Khoo, H.E. (1994). A review of stonefish venoms and toxins. Pharmacology and Therapeutics 64 (3) : 509-528. ScholarBank@NUS Repository. https://doi.org/10.1016/0163-7258(94)90022-1
Abstract:	Venoms from stonefish (genus Synanceja) have marked effects on the cardiovascular and neuromuscular systems and on vascular permeability; the venoms also exhibit haemolytic and hyaluronidase activity. Recently, a toxic protein, stonustoxin (SNTX), was purified from the venom of S. horrida: the primary lethal action of SNTX has been attributed to its potent endothelium-dependent vasorelaxant activity causing a rapid, marked and irreversible hypotension; the other actions of SNTX resemble those of the stonefish crude venoms.
Source Title:	Pharmacology and Therapeutics
URI:	http://scholarbank.nus.edu.sg/handle/10635/33949
ISSN:	01637258
DOI:	10.1016/0163-7258(94)90022-1
Appears in Collections:	Staff Publications

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