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Title: A review of stonefish venoms and toxins
Authors: Gwee, M.C.E. 
Low, K.S.Y.
Gopalakrishnakone, P. 
Yuen, R.
Khoo, H.E. 
Keywords: endothelium-dependent vasorelaxation
stonefish (Synanceja)
systemic effects
Issue Date: 1994
Citation: Gwee, M.C.E., Low, K.S.Y., Gopalakrishnakone, P., Yuen, R., Khoo, H.E. (1994). A review of stonefish venoms and toxins. Pharmacology and Therapeutics 64 (3) : 509-528. ScholarBank@NUS Repository.
Abstract: Venoms from stonefish (genus Synanceja) have marked effects on the cardiovascular and neuromuscular systems and on vascular permeability; the venoms also exhibit haemolytic and hyaluronidase activity. Recently, a toxic protein, stonustoxin (SNTX), was purified from the venom of S. horrida: the primary lethal action of SNTX has been attributed to its potent endothelium-dependent vasorelaxant activity causing a rapid, marked and irreversible hypotension; the other actions of SNTX resemble those of the stonefish crude venoms.
Source Title: Pharmacology and Therapeutics
ISSN: 01637258
DOI: 10.1016/0163-7258(94)90022-1
Appears in Collections:Staff Publications

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