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https://doi.org/10.1016/S0048-9697(97)00288-X
DC Field | Value | |
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dc.title | Serum DDT and DDE levels in Singapore general population | |
dc.contributor.author | Luo, X.W. | |
dc.contributor.author | Foo, S.C. | |
dc.contributor.author | Ong, H.Y. | |
dc.date.accessioned | 2012-04-02T06:53:49Z | |
dc.date.available | 2012-04-02T06:53:49Z | |
dc.date.issued | 1997 | |
dc.identifier.citation | Luo, X.W., Foo, S.C., Ong, H.Y. (1997). Serum DDT and DDE levels in Singapore general population. Science of the Total Environment 208 (1-2) : 97-104. ScholarBank@NUS Repository. https://doi.org/10.1016/S0048-9697(97)00288-X | |
dc.identifier.issn | 00489697 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/31819 | |
dc.description.abstract | A simple and fast method was used to determine 1,1'-(2,2,2- trichloroethylene)-bis(4-chlorobenzene) (DDT) and 1,1'-(2,2- dichloroethylidene)-bis(4-chlorobenzene) (DDE) in blood serum. Serum samples pre-treated with formic acid were extracted with n-hexane and determined by gas chromatography (GC-ECD), using PTE-5 capillary column. Detection limits for DDT and DDE were 0.5 ppb. Recovery with a fortified pooled sample at 1 ppb level was 107.0% for DDT and 106.0% for DDE. At 10 ppb level, the recoveries for DDT and DDE were 96.1% and 92.7%, respectively. Eighty-nine random blood samples collected from volunteers were analyzed. The geometric mean (GM) serum level of DDT was 1.9 ppb (0.2-8.9 ppb) and that of DDE was 10.8 ppb (1.5-88.1 ppb). There was a positive correlation between DDE and DDT level (r = 0.33, P < 0.01). The serum DDE level was positively correlated with age (r = 0.49, P < 0.01) and DDT x Age (r = 0.62, P < 0.01). No correlation was observed between DDT and age. These results suggest that DDE, a metabolite of DDT, is cumulative in the body. Therefore blood DDE could be used as a cumulative exposure marker for DDT, whereas blood DDT may be used to reflect its recent exposure. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/S0048-9697(97)00288-X | |
dc.source | Scopus | |
dc.subject | Biological indicator | |
dc.subject | DDT exposure | |
dc.subject | Serum DDE | |
dc.subject | Serum DDT | |
dc.subject | Singapore | |
dc.type | Article | |
dc.contributor.department | COMMUNITY,OCCUPATIONAL & FAMILY MEDICINE | |
dc.description.doi | 10.1016/S0048-9697(97)00288-X | |
dc.description.sourcetitle | Science of the Total Environment | |
dc.description.volume | 208 | |
dc.description.issue | 1-2 | |
dc.description.page | 97-104 | |
dc.description.coden | STEVA | |
dc.identifier.isiut | 000072230000011 | |
Appears in Collections: | Staff Publications |
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