Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.transproceed.2004.11.062
DC FieldValue
dc.titleTransplantation of neonatal porcine islets and Sertoli cells into nonimmunosuppressed nonhuman primates
dc.contributor.authorIsaac, J.R.
dc.contributor.authorKhoo, A.
dc.contributor.authorCalne, R.
dc.contributor.authorWang, D.Z.
dc.contributor.authorLee, K.O.
dc.contributor.authorSalto-Tellez, M.
dc.contributor.authorSkinner, S.
dc.contributor.authorElliot, R.
dc.contributor.authorGarkavenko, O.
dc.date.accessioned2012-02-01T09:15:55Z
dc.date.available2012-02-01T09:15:55Z
dc.date.issued2005
dc.identifier.citationIsaac, J.R., Khoo, A., Calne, R., Wang, D.Z., Lee, K.O., Salto-Tellez, M., Skinner, S., Elliot, R., Garkavenko, O. (2005). Transplantation of neonatal porcine islets and Sertoli cells into nonimmunosuppressed nonhuman primates. Transplantation Proceedings 37 (1) : 487-488. ScholarBank@NUS Repository. https://doi.org/10.1016/j.transproceed.2004.11.062
dc.identifier.issn00411345
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/30513
dc.description.abstractA Mexican group reported transplantation of cocultured neonatal porcine islets and Sertoli cells resulting in insulin independence in nonimmunosuppressed type 1 diabetes patients. We have transplanted similar islets alone (naked islets) or cocultured islets with sertoli cells (islet/sertoli cells) into an omental site and other locations of seven nondiabetic, nonimmunosuppressed, nonhuman primates. Porcine endogenous retrovirus was not detected in recipient blood 8 weeks after porcine islet grafts, and porcine C-peptide was detected at a very low level in all animals. Histology examination failed to demonstrate obviously recognizable islets, but in the animals transplanted with islet/Sertoli cells at the omentum site, there were some surviving glucagons, pan-cytokeratin, and inhibin stained cells at 8 weeks. © 2005 by Elsevier Inc. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.transproceed.2004.11.062
dc.sourceScopus
dc.typeConference Paper
dc.contributor.departmentPATHOLOGY
dc.contributor.departmentMEDICINE
dc.contributor.departmentSURGERY
dc.description.doi10.1016/j.transproceed.2004.11.062
dc.description.sourcetitleTransplantation Proceedings
dc.description.volume37
dc.description.issue1
dc.description.page487-488
dc.description.codenTRPPA
dc.identifier.isiut000228091300160
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.