Please use this identifier to cite or link to this item: https://doi.org/10.1016/0885-4505(91)90037-L
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dc.titleEffects of dietary palm oil on serum lipid peroxidation, antithrombin III, plasma cyclic AMP, and platelet aggregation
dc.contributor.authorPereira, T.A.
dc.contributor.authorShahi, G.S.
dc.contributor.authorDas, N.P.
dc.date.accessioned2011-12-07T08:16:38Z
dc.date.available2011-12-07T08:16:38Z
dc.date.issued1991
dc.identifier.citationPereira, T.A., Shahi, G.S., Das, N.P. (1991). Effects of dietary palm oil on serum lipid peroxidation, antithrombin III, plasma cyclic AMP, and platelet aggregation. Biochemical Medicine and Metabolic Biology 45 (3) : 326-332. ScholarBank@NUS Repository. https://doi.org/10.1016/0885-4505(91)90037-L
dc.identifier.issn08854505
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/29705
dc.description.abstractIntravascular thrombus formation in association with lipid depositions in the arterial wall is thought to be involved in the process of atheroma formation. We have previously shown the beneficial effect of palm oil on the serum lipid profile (2) resulting in a lowering of serum triacylglycerol and an elevation of the HDL/LDL ratio. The present study investigates the effect of dietary palm oil on the biochemical parameters associated with clotting and platelet aggregation in young rats (70 g body wt) fed a palm oil diet over a period of 10 weeks. Palm oil-fed rats showed significantly lower levels of fibrinogen and serum lipid peroxide and elevated AtIII levels resulting in a prolongation of clotting time. Reduced platelet aggregation and ATP release associated with a prolongation of bleeding time were also found. These findings, together with our earlier findings on the effect of palm oil on the serum lipid profile, suggest that dietary palm oil may be antithrombotic as well as beneficial in preventing the deposition of lipids on the vessel wall and may, therefore, be protective against the development of atherosclerosis.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/0885-4505(91)90037-L
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentBIOCHEMISTRY
dc.contributor.departmentPHYSIOLOGY
dc.description.doi10.1016/0885-4505(91)90037-L
dc.description.sourcetitleBiochemical Medicine and Metabolic Biology
dc.description.volume45
dc.description.issue3
dc.description.page326-332
dc.description.codenBMMBE
dc.identifier.isiutA1991FQ18600006
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