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Title: Medicinal plants and antioxidants: What do we learn from cell culture and Caenorhabditis elegans studies?
Authors: Tang, S.Y. 
Halliwell, B. 
Keywords: Antioxidants
Caenorhabditis elegans
Cell culture
Oxidative stress
Traditional medicinal plants
Issue Date: 2010
Citation: Tang, S.Y., Halliwell, B. (2010). Medicinal plants and antioxidants: What do we learn from cell culture and Caenorhabditis elegans studies?. Biochemical and Biophysical Research Communications 394 (1) : 1-5. ScholarBank@NUS Repository.
Abstract: Traditional medicinal plants have a long history of therapeutic use. The beneficial health effects of medicinal plants rich in polyphenols are often attributed to their potent antioxidant activities, as established in vitro, since diets rich in polyphenols are epidemiologically associated with a decreased incidence of age-related diseases in humans. However, medicinal plants may also exert pro-oxidant effects that up-regulate endogenous protective enzymes. Care is needed when studying the biological effects of medicinal plants in cell culture because some polyphenols oxidize readily in culture media. This review summarizes the data we have obtained from in vitro and in vivo (Caenorhabditis elegans) studies examining the diverse effects of traditional medicinal plants and their modes of action. © 2010 Elsevier Inc. All rights reserved.
Source Title: Biochemical and Biophysical Research Communications
ISSN: 0006291X
DOI: 10.1016/j.bbrc.2010.02.137
Appears in Collections:Staff Publications

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