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|Title:||Use of endothelial progenitor cell capture stent (Genous Bio-Engineered R Stent) during primary percutaneous coronary intervention in acute myocardial infarction: Intermediate- to long-term clinical follow-up||Authors:||Co, M.
|Issue Date:||2008||Citation:||Co, M., Tay, E., Lee, C.H., Poh, K.K., Low, A., Lim, Y.T., Tan, H.C., Lim, J., Lim, I.H. (2008). Use of endothelial progenitor cell capture stent (Genous Bio-Engineered R Stent) during primary percutaneous coronary intervention in acute myocardial infarction: Intermediate- to long-term clinical follow-up. American Heart Journal 155 (1) : 128-132. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ahj.2007.08.031||Abstract:||Aims: We assessed the use of the endothelial progenitor cell (EPC) capture stent in primary percutaneous intervention in ST-elevation myocardial infarction (STEMI). Methods and Results: One hundred and twenty patients with acute STEMI without cardiogenic shock received 129 EPC capture stents. Procedural success was achieved in 95% of patients. Dual antiplatelet therapy was given for a month and statin therapy started immediately after the procedure. The study end points are major adverse cardiac events inhospital and at 30 days, 6 months, and 1 year. Hypertension was present in 47.5% and diabetes mellitus in 30% of the patients. The left anterior descending artery was the treated artery in 54% of the patients. Mean lesion length was 17.4 ± 7.15 mm with mean reference vessel diameter of 3.18 ± 0.6 mm. Platelet glycoprotein IIb/IIIa inhibitor was used in 14% of patients and 58% had thrombosuction before stent implantation. Ninety-five percent of patients achieved Thrombolysis in Myocardial Infarction 3 flow with cumulative major adverse cardiac event rate at 1.6% inhospital, 4.2% at 30 days, 5.8% at 6 months, and 9.2% at 1 year. There was 1 patient each with acute and subacute stent thrombosis but no incidence of late stent thrombosis. Conclusion: Using EPC capture stent during primary percutaneous coronary intervention for STEMI is feasible and safe. © 2008.||Source Title:||American Heart Journal||URI:||http://scholarbank.nus.edu.sg/handle/10635/26770||ISSN:||00028703
|Appears in Collections:||Staff Publications|
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