Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.echo.2007.05.027
DC FieldValue
dc.titleThe Mitral Annular Middiastolic Velocity Curve: Functional Correlates and Clinical Significance in Patients with Left Ventricular Hypertrophy
dc.contributor.authorLam, C.S.P.
dc.contributor.authorHan, L.
dc.contributor.authorYang, H.
dc.contributor.authorLing, L.H.
dc.contributor.authorOh, J.K.
dc.date.accessioned2011-09-27T05:15:01Z
dc.date.available2011-09-27T05:15:01Z
dc.date.issued2008
dc.identifier.citationLam, C.S.P., Han, L., Yang, H., Ling, L.H., Oh, J.K. (2008). The Mitral Annular Middiastolic Velocity Curve: Functional Correlates and Clinical Significance in Patients with Left Ventricular Hypertrophy. Journal of the American Society of Echocardiography 21 (2) : 165-170. ScholarBank@NUS Repository. https://doi.org/10.1016/j.echo.2007.05.027
dc.identifier.issn08947317
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/26727
dc.description.abstractBackground: Little is known regarding the tissue Doppler characteristics and clinical significance of mitral annular motion during diastasis (L' wave). Methods: In consecutive patients with left ventricular hypertrophy and normal ejection fraction, standard Doppler and Doppler tissue imaging were performed. Patients were followed up for heart failure (HF) hospitalization. Results: Of 177 patients, 53 (30%) had an L′, detected most frequently at the lateral mitral annulus, whereas 35 (20%) had middiastolic transmitral flow (L wave), which almost invariably coexisted with the L'. The L' predicted increased left ventricular filling pressure with 74% sensitivity and 82% specificity, and increased risk of future HF (hazard ratio 3.9 [P = .030]), even after adjusting for baseline clinical differences (hazard ratio 6.5 [P = .024]). When associated with an L wave, HF risk increased further. Conclusions: Middiastolic annular motion, detectable in almost a third of patients with left ventricular hypertrophy, may be an early marker of diastolic dysfunction and a prognostic marker for HF. © 2008 American Society of Echocardiography.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.echo.2007.05.027
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMEDICINE
dc.description.doi10.1016/j.echo.2007.05.027
dc.description.sourcetitleJournal of the American Society of Echocardiography
dc.description.volume21
dc.description.issue2
dc.description.page165-170
dc.identifier.isiut000253423500012
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

10
checked on Feb 18, 2020

WEB OF SCIENCETM
Citations

8
checked on Feb 10, 2020

Page view(s)

194
checked on Feb 19, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.