Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.echo.2007.05.027
DC Field | Value | |
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dc.title | The Mitral Annular Middiastolic Velocity Curve: Functional Correlates and Clinical Significance in Patients with Left Ventricular Hypertrophy | |
dc.contributor.author | Lam, C.S.P. | |
dc.contributor.author | Han, L. | |
dc.contributor.author | Yang, H. | |
dc.contributor.author | Ling, L.H. | |
dc.contributor.author | Oh, J.K. | |
dc.date.accessioned | 2011-09-27T05:15:01Z | |
dc.date.available | 2011-09-27T05:15:01Z | |
dc.date.issued | 2008 | |
dc.identifier.citation | Lam, C.S.P., Han, L., Yang, H., Ling, L.H., Oh, J.K. (2008). The Mitral Annular Middiastolic Velocity Curve: Functional Correlates and Clinical Significance in Patients with Left Ventricular Hypertrophy. Journal of the American Society of Echocardiography 21 (2) : 165-170. ScholarBank@NUS Repository. https://doi.org/10.1016/j.echo.2007.05.027 | |
dc.identifier.issn | 08947317 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/26727 | |
dc.description.abstract | Background: Little is known regarding the tissue Doppler characteristics and clinical significance of mitral annular motion during diastasis (L' wave). Methods: In consecutive patients with left ventricular hypertrophy and normal ejection fraction, standard Doppler and Doppler tissue imaging were performed. Patients were followed up for heart failure (HF) hospitalization. Results: Of 177 patients, 53 (30%) had an L′, detected most frequently at the lateral mitral annulus, whereas 35 (20%) had middiastolic transmitral flow (L wave), which almost invariably coexisted with the L'. The L' predicted increased left ventricular filling pressure with 74% sensitivity and 82% specificity, and increased risk of future HF (hazard ratio 3.9 [P = .030]), even after adjusting for baseline clinical differences (hazard ratio 6.5 [P = .024]). When associated with an L wave, HF risk increased further. Conclusions: Middiastolic annular motion, detectable in almost a third of patients with left ventricular hypertrophy, may be an early marker of diastolic dysfunction and a prognostic marker for HF. © 2008 American Society of Echocardiography. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.echo.2007.05.027 | |
dc.source | Scopus | |
dc.type | Article | |
dc.contributor.department | MEDICINE | |
dc.description.doi | 10.1016/j.echo.2007.05.027 | |
dc.description.sourcetitle | Journal of the American Society of Echocardiography | |
dc.description.volume | 21 | |
dc.description.issue | 2 | |
dc.description.page | 165-170 | |
dc.identifier.isiut | 000253423500012 | |
Appears in Collections: | Staff Publications |
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