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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.vaccine.2010.01.020
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dc.titleEffect of probiotic supplementation in the first 6 months of life on specific antibody responses to infant Hepatitis B vaccination
dc.contributor.authorSoh, S.E.
dc.contributor.authorOng, D.Q.R.
dc.contributor.authorGerez, I.
dc.contributor.authorShek, L.P.-C.
dc.contributor.authorLee, B.W.
dc.contributor.authorAw, M.
dc.contributor.authorZhang, X.
dc.contributor.authorChollate, P.
dc.date.accessioned2011-08-16T07:52:37Z
dc.date.available2011-08-16T07:52:37Z
dc.date.issued2010
dc.identifier.citationSoh, S.E., Ong, D.Q.R., Gerez, I., Shek, L.P.-C., Lee, B.W., Aw, M., Zhang, X., Chollate, P. (2010). Effect of probiotic supplementation in the first 6 months of life on specific antibody responses to infant Hepatitis B vaccination. Vaccine 28 (14) : 2577-2579. ScholarBank@NUS Repository. https://doi.org/10.1016/j.vaccine.2010.01.020
dc.identifier.issn0264410X
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/25749
dc.description.abstractProbiotics have been shown to enhance specific immune responses to vaccines. We aim to assess the effect of probiotic supplementation on specific IgG antibody responses to Hepatitis B (HepB) vaccination in infants. Compared to controls, probiotic supplementation improved HepB surface antibody responses in subjects receiving monovalent doses of HepB vaccine at 0, 1 month and a DTPa-HepB combination vaccine at 6 months [placebo (n = 28): 187.97 (180.70-195.24), probiotic (n = 29): 345.70 (339.41-351.99) mIU/ml] (p = 0.069), but not those who received 3 monovalent doses [placebo (n = 68): 302.34 (296.31-308.37), probiotic (n = 77): 302.06 (296.31-307.81) mIU/ml] (p = 0.996). Probiotics may enhance specific antibody responses in infants receiving certain Hepatitis B vaccine schedules. © 2010 Elsevier Ltd. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.vaccine.2010.01.020
dc.sourceScopus
dc.subjectHepatitis B
dc.subjectProbiotics
dc.subjectVaccination
dc.typeArticle
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.contributor.departmentPAEDIATRICS
dc.description.doi10.1016/j.vaccine.2010.01.020
dc.description.sourcetitleVaccine
dc.description.volume28
dc.description.issue14
dc.description.page2577-2579
dc.identifier.isiut000276505700001
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