Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ajo.2009.04.006
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dc.titleRelationship of Retinal Vascular Caliber with Optic Disc and Macular Structure
dc.contributor.authorLim, L.S.
dc.contributor.authorWong, T.Y.
dc.contributor.authorSaw, S.M.
dc.contributor.authorCheung, N.
dc.contributor.authorMitchell, P.
dc.date.accessioned2011-07-26T03:01:48Z
dc.date.available2011-07-26T03:01:48Z
dc.date.issued2009
dc.identifier.citationLim, L.S., Wong, T.Y., Saw, S.M., Cheung, N., Mitchell, P. (2009). Relationship of Retinal Vascular Caliber with Optic Disc and Macular Structure. American Journal of Ophthalmology 148 (3) : 368-375. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ajo.2009.04.006
dc.identifier.issn00029394
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/24617
dc.description.abstractPurpose: To examine the relationships of retinal vascular caliber with optic disc, macular, and retinal nerve fiber layer (RNFL) characteristics as measured with optical coherence tomography (OCT). Design: Observational cross-sectional study. Methods: This study included a subset of healthy children enrolled in the Singapore Cohort Study of the Risk Factors of Myopia (SCORM). Optic disc, macular, and RNFL morphology were measured with Stratus OCT 3. Digital retinal photography was performed and retinal arteriolar and venular caliber measured using validated imaging software. Results: One hundred and four children (mean age 11.51 ± 0.52 years; 50% male) were included. In multivariate analyses, smaller horizontal integrated rim width and rim area were associated with narrower retinal arterioles and venules (all P < .05), and shorter horizontal rim length was associated with narrower venules (P = .04). Optic disc diameter was not associated with arteriolar or venular caliber. Larger vertical cup-to-disc ratios and cup-to-disc-area ratios were associated with narrower venules but not arterioles (P = .01 and P = .003, respectively). A thinner average RNFL measurement was associated with narrower arterioles and venules, and smaller total macular volume was associated with narrower venules. Conclusions: Thinner optic disc rims and RNFL measurements were associated with narrower retinal arterioles and venules, and larger cup-to-disc ratios with narrower venules. These findings suggest that retinal vessel caliber varies systematically with morphologic differences in the optic nerve head, retina, and macula. © 2009 Elsevier Inc. All rights reserved.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ajo.2009.04.006
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1016/j.ajo.2009.04.006
dc.description.sourcetitleAmerican Journal of Ophthalmology
dc.description.volume148
dc.description.issue3
dc.description.page368-375
dc.identifier.isiut000269755400007
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