Please use this identifier to cite or link to this item:
https://doi.org/10.3390/cells7030018
DC Field | Value | |
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dc.title | MiroWorking beyond Mitochondria and Microtubules | |
dc.contributor.author | Tang, Bor Luen | |
dc.date.accessioned | 2023-11-14T04:39:58Z | |
dc.date.available | 2023-11-14T04:39:58Z | |
dc.date.issued | 2018-03 | |
dc.identifier.citation | Tang, Bor Luen (2018-03). MiroWorking beyond Mitochondria and Microtubules. CELLS 7 (3). ScholarBank@NUS Repository. https://doi.org/10.3390/cells7030018 | |
dc.identifier.issn | 2073-4409 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/245927 | |
dc.description.abstract | The small GTPase Miro is best known for its regulation of mitochondrial movement by engaging with the microtubule-based motor proteins kinesin and dynein. Very recent findings have now showed that Miro also targets peroxisomes and regulates microtubule-dependent peroxisome motility. Moreover, Miro recruits and stabilizes the myosin motor Myo19 at the mitochondria to enable actin-based mitochondria movement, which is important for mitochondrial segregation during mitosis. Miro thus has much broader functions that previously known, and these new findings may have important implications on disease pathology. | |
dc.language.iso | en | |
dc.publisher | MDPI | |
dc.source | Elements | |
dc.subject | Science & Technology | |
dc.subject | Life Sciences & Biomedicine | |
dc.subject | Cell Biology | |
dc.subject | Mitochondrial Rho (Miro) | |
dc.subject | mitochondria | |
dc.subject | peroxisome | |
dc.subject | microtubules | |
dc.subject | actin | |
dc.subject | TRANSPORT | |
dc.subject | MIRO | |
dc.subject | PHOSPHORYLATION | |
dc.subject | MOVEMENT | |
dc.subject | PROTEINS | |
dc.subject | DYNAMICS | |
dc.subject | MILTON | |
dc.subject | MODEL | |
dc.subject | RAB10 | |
dc.type | Article | |
dc.date.updated | 2023-11-12T07:03:10Z | |
dc.contributor.department | DEAN'S OFFICE (NGS FOR INTGR SCI & ENGG) | |
dc.description.doi | 10.3390/cells7030018 | |
dc.description.sourcetitle | CELLS | |
dc.description.volume | 7 | |
dc.description.issue | 3 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
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Miro-Working beyond Mitochondria and Microtubules. .pdf | 627.88 kB | Adobe PDF | OPEN | Published | View/Download |
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