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Please use this identifier to cite or link to this item: https://doi.org/10.3390/ijms24010713
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dc.titleThe Management of Ocular Surface Squamous Neoplasia (OSSN)
dc.contributor.authorYeoh, Clarice HY
dc.contributor.authorLee, Jerome JR
dc.contributor.authorLim, Blanche XH
dc.contributor.authorSundar, Gangadhara
dc.contributor.authorMehta, Jodhbir S
dc.contributor.authorChan, Anita SY
dc.contributor.authorLim, Dawn KA
dc.contributor.authorWatson, Stephanie L
dc.contributor.authorHonavar, Santosh G
dc.contributor.authorManotosh, Ray
dc.contributor.authorLim, Chris HL
dc.date.accessioned2023-11-06T07:43:23Z
dc.date.available2023-11-06T07:43:23Z
dc.date.issued2023-01
dc.identifier.citationYeoh, Clarice HY, Lee, Jerome JR, Lim, Blanche XH, Sundar, Gangadhara, Mehta, Jodhbir S, Chan, Anita SY, Lim, Dawn KA, Watson, Stephanie L, Honavar, Santosh G, Manotosh, Ray, Lim, Chris HL (2023-01). The Management of Ocular Surface Squamous Neoplasia (OSSN). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24 (1). ScholarBank@NUS Repository. https://doi.org/10.3390/ijms24010713
dc.identifier.issn1661-6596
dc.identifier.issn1422-0067
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/245760
dc.description.abstractThe rise of primary topical monotherapy with chemotherapeutic drugs and immunomodulatory agents represents an increasing recognition of the medical management of ocular surface squamous neoplasia (OSSN), which may replace surgery as the standard of care in the future. Currently, there is no consensus regarding the best way to manage OSSN with no existing guidelines to date. This paper seeks to evaluate evidence surrounding available treatment modalities and proposes an approach to management. The approach will guide ophthalmologists in selecting the most appropriate treatment regime based on patient and disease factors to minimize treatment related morbidity and improve OSSN control. Further work can be done to validate this algorithm and to develop formal guidelines to direct the management of OSSN.
dc.language.isoen
dc.publisherMDPI
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectPhysical Sciences
dc.subjectBiochemistry & Molecular Biology
dc.subjectChemistry, Multidisciplinary
dc.subjectChemistry
dc.subjectocular surface squamous neoplasia
dc.subjectmanagement
dc.subjecttopical chemotherapy
dc.subject5-fluorouracil (5-FU)
dc.subjectmitomycin C (MMC)
dc.subjectinterferon alfa (INF alpha)
dc.subjectsurgical excision
dc.subjectadjuncts
dc.subjectTOPICAL MITOMYCIN-C
dc.subjectCORNEAL INTRAEPITHELIAL NEOPLASIA
dc.subjectAMNIOTIC MEMBRANE TRANSPLANTATION
dc.subjectLIMBAL EPITHELIAL TRANSPLANTATION
dc.subjectOPTICAL COHERENCE TOMOGRAPHY
dc.subjectVIVO CONFOCAL MICROSCOPY
dc.subjectHUMAN PAPILLOMA-VIRUS
dc.subjectCELL CARCINOMA
dc.subjectSUBCONJUNCTIVAL RANIBIZUMAB
dc.subjectINTRAOCULAR INVASION
dc.typeReview
dc.date.updated2023-11-06T05:27:06Z
dc.contributor.departmentOPHTHALMOLOGY
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.description.doi10.3390/ijms24010713
dc.description.sourcetitleINTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
dc.description.volume24
dc.description.issue1
dc.published.statePublished
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