EFFECT OF LVAD OUTFLOW GRAFT POISITIONING ON AORTIC HEMODYNAMICS

Abstract

Heart failure is a global health issue with significant implications for healthcare systems. Left ventricular assist devices (LVADs) provide mechanical support for patients with severe heart failure. However, the placement of the LVAD outflow graft within the aorta carries significant implications for hemodynamics. This study utilized computational fluid dynamics simulations to investigate the impact of different LVAD outflow graft locations on aortic hemodynamics. It is found that height and inclination angle played similar roles in controlling retrograde flow to the aortic root, while the azimuthal angle primarily determined the rotational direction of blood flow in the aortic arch. An innovative aspect of this study was the incorporation of valve morphology, which addressed the current research gap. It provides a comprehensive understanding of the correlation between the LVAD outflow cannula positioning and its hemodynamic impact for clinicians to effectively enhance patient outcomes.