Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.ultsonch.2023.106466
DC Field | Value | |
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dc.title | Ultrasound-assisted formation of chitosan-glucose Maillard reaction products to fabricate nanoparticles with enhanced antioxidant activity | |
dc.contributor.author | Viturat, S | |
dc.contributor.author | Thongngam, M | |
dc.contributor.author | Lumdubwong, N | |
dc.contributor.author | Zhou, W | |
dc.contributor.author | Klinkesorn, U | |
dc.date.accessioned | 2023-07-24T12:20:17Z | |
dc.date.available | 2023-07-24T12:20:17Z | |
dc.date.issued | 2023-07-01 | |
dc.identifier.citation | Viturat, S, Thongngam, M, Lumdubwong, N, Zhou, W, Klinkesorn, U (2023-07-01). Ultrasound-assisted formation of chitosan-glucose Maillard reaction products to fabricate nanoparticles with enhanced antioxidant activity. Ultrasonics Sonochemistry 97 : 106466-. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ultsonch.2023.106466 | |
dc.identifier.issn | 1350-4177 | |
dc.identifier.issn | 1873-2828 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/243376 | |
dc.description.abstract | The influence of ultrasonic processing parameters including reaction temperature (60, 70 and 80 °C), time (0, 15, 30, 45 and 60 min) and amplitude (70, 85 and 100%) on the formation and antioxidant activity of Maillard reaction products (MRPs) in a solution of chitosan and glucose (1.5 wt% at mass ratio of 1:1) was investigated. Selected chitosan-glucose MRPs were further studied to determine the effects of solution pH on the fabrication of antioxidative nanoparticles by ionic crosslinking with sodium tripolyphosphate. Results from FT-IR analysis, zeta-potential determination and color measurement indicated that chitosan-glucose MRPs with improved antioxidant activity were successfully produced using an ultrasound-assisted process. The highest antioxidant activity of MRPs was observed at the reaction temperature, time and amplitude of 80 °C, 60 min and 70%, respectively, with ∼ 34.5 and ∼20.2 μg Trolox mL−1 for DPPH scavenging activity and reducing power, respectively. The pH of both MRPs and tripolyphosphate solutions significantly influenced the fabrication and characteristics of the nanoparticles. Using chitosan-glucose MRPs and tripolyphosphate solution at pH 4.0 generated nanoparticles with enhanced antioxidant activity (∼1.6 and ∼ 1.2 μg Trolox mg−1 for reducing power and DPPH scavenging activity, respectively) with the highest percentage yield (∼59%), intermediate particle size (∼447 nm) and zeta-potential ∼ 19.6 mV. These results present innovative findings for the fabrication of chitosan-based nanoparticles with enhanced antioxidant activity by pre-conjugation with glucose via the Maillard reaction aided by ultrasonic processing. | |
dc.publisher | Elsevier BV | |
dc.source | Elements | |
dc.subject | Antioxidant activity | |
dc.subject | Chitosan nanoparticle | |
dc.subject | FTIR-analysis | |
dc.subject | Maillard reaction product | |
dc.subject | Tripolyphosphate cross-linking | |
dc.subject | Ultrasound-assisted process | |
dc.subject | Antioxidants | |
dc.subject | Chitosan | |
dc.subject | Glucose | |
dc.subject | Spectroscopy, Fourier Transform Infrared | |
dc.subject | Maillard Reaction | |
dc.subject | Glycation End Products, Advanced | |
dc.subject | Nanoparticles | |
dc.type | Article | |
dc.date.updated | 2023-07-22T22:53:15Z | |
dc.contributor.department | FOOD SCIENCE & TECHNOLOGY | |
dc.description.doi | 10.1016/j.ultsonch.2023.106466 | |
dc.description.sourcetitle | Ultrasonics Sonochemistry | |
dc.description.volume | 97 | |
dc.description.page | 106466- | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
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Ultrasound-assisted formation of chitosan-glucose Maillard reaction products to fabricate nanoparticles with enhanced antiox.pdf | 7.56 MB | Adobe PDF | OPEN | Published | View/Download |
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