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Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.oraloncology.2016.07.010
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dc.titleThe other side of the coin: Leveraging Epstein-Barr virus in research and therapy
dc.contributor.authorYu, Fenggang
dc.contributor.authorTan, Wei Jian
dc.contributor.authorLu, Yanan
dc.contributor.authorMacAry, Paul A
dc.contributor.authorLoh, Kwok Seng
dc.date.accessioned2023-05-18T09:06:31Z
dc.date.available2023-05-18T09:06:31Z
dc.date.issued2016-09-01
dc.identifier.citationYu, Fenggang, Tan, Wei Jian, Lu, Yanan, MacAry, Paul A, Loh, Kwok Seng (2016-09-01). The other side of the coin: Leveraging Epstein-Barr virus in research and therapy. ORAL ONCOLOGY 60 : 112-117. ScholarBank@NUS Repository. https://doi.org/10.1016/j.oraloncology.2016.07.010
dc.identifier.issn1368-8375
dc.identifier.issn1879-0593
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/239503
dc.description.abstractEpstein-Barr virus is (EBV) a ubiquitous virus prevalent in 90% of the human population. Transmitted through infected saliva, EBV is the causative agent of infectious mononucleosis (IM) and is further implicated in malignancies of lymphoid and epithelial origins. In the past few decades, research efforts primarily focused on dissecting the mechanism of EBV-induced oncogenesis. Here, we present an alternate facet of the oncovirus EBV, on its applications in research and therapy. Finally, discussions on the prospective utilization of EBV in nasopharyngeal carcinoma (NPC) diagnosis and therapy will also be presented.
dc.language.isoen
dc.publisherELSEVIER SCIENCE BV
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectOncology
dc.subjectDentistry, Oral Surgery & Medicine
dc.subjectEpstein-Barr virus
dc.subjectResearch and therapy
dc.subjectNasopharyngeal carcinoma
dc.subjectLymphoma
dc.subjectRECOMBINANT PROTEIN-PRODUCTION
dc.subjectHUMAN MONOCLONAL-ANTIBODIES
dc.subjectCYTOTOXIC T-CELLS
dc.subjectMEMORY B-CELLS
dc.subjectNASOPHARYNGEAL CARCINOMA
dc.subjectTRANSIENT TRANSFECTION
dc.subjectADOPTIVE TRANSFER
dc.subjectGENE-EXPRESSION
dc.subjectHIGH-LEVEL
dc.subjectEBV DNA
dc.typeReview
dc.date.updated2023-05-18T03:54:40Z
dc.contributor.departmentMICROBIOLOGY AND IMMUNOLOGY
dc.contributor.departmentOTOLARYNGOLOGY
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1016/j.oraloncology.2016.07.010
dc.description.sourcetitleORAL ONCOLOGY
dc.description.volume60
dc.description.page112-117
dc.published.statePublished
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