Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.bbrc.2015.12.124
DC Field | Value | |
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dc.title | Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis | |
dc.contributor.author | Halliwell, Barry | |
dc.contributor.author | Cheah, Irwin K | |
dc.contributor.author | Drum, Chester L | |
dc.date.accessioned | 2022-11-18T05:08:23Z | |
dc.date.available | 2022-11-18T05:08:23Z | |
dc.date.issued | 2016-02-05 | |
dc.identifier.citation | Halliwell, Barry, Cheah, Irwin K, Drum, Chester L (2016-02-05). Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 470 (2) : 245-250. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bbrc.2015.12.124 | |
dc.identifier.issn | 0006291X | |
dc.identifier.issn | 10902104 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/234702 | |
dc.description.abstract | Ergothioneine (ET) is a diet-derived, thiolated derivative of histidine with antioxidant properties. Although ET is produced only by certain fungi and bacteria, it can be found at high concentrations in certain human and animal tissues and is absorbed through a specific, high affinity transporter (OCTN1). In liver, heart, joint and intestinal injury, elevated ET concentrations have been observed in injured tissues. The physiological role of ET remains unclear. We thus review current literature to generate a specific hypothesis: that the accumulation of ET in vivo is an adaptive mechanism, involving the regulated uptake and concentration of an exogenous natural compound to minimize oxidative damage. | |
dc.language.iso | en | |
dc.publisher | ACADEMIC PRESS INC ELSEVIER SCIENCE | |
dc.source | Elements | |
dc.subject | Science & Technology | |
dc.subject | Life Sciences & Biomedicine | |
dc.subject | Biochemistry & Molecular Biology | |
dc.subject | Biophysics | |
dc.subject | Reactive oxygen species | |
dc.subject | Antioxidant | |
dc.subject | Ergothioneine | |
dc.subject | Adaptation | |
dc.subject | OCTN1 | |
dc.subject | Mushrooms | |
dc.subject | ORGANIC CATION TRANSPORTER | |
dc.subject | RED-BLOOD-CELLS | |
dc.subject | RHEUMATOID-ARTHRITIS | |
dc.subject | OXIDATIVE STRESS | |
dc.subject | CROHNS-DISEASE | |
dc.subject | AMINO-ACID | |
dc.subject | GENETIC-VARIATIONS | |
dc.subject | 503F VARIANT | |
dc.subject | SLC22A5 GENE | |
dc.subject | HIGH-FAT | |
dc.type | Review | |
dc.date.updated | 2022-11-18T02:38:39Z | |
dc.contributor.department | BIOCHEMISTRY | |
dc.contributor.department | MEDICINE | |
dc.description.doi | 10.1016/j.bbrc.2015.12.124 | |
dc.description.sourcetitle | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | |
dc.description.volume | 470 | |
dc.description.issue | 2 | |
dc.description.page | 245-250 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
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1-s2.0-S0006291X15311281-main.pdf | 800.24 kB | Adobe PDF | CLOSED | Published |
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