1. ScholarBank@NUS
  2. 1. Staff
  3. Elements
Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.bbrc.2015.12.124
DC FieldValue
dc.titleErgothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis
dc.contributor.authorHalliwell, Barry
dc.contributor.authorCheah, Irwin K
dc.contributor.authorDrum, Chester L
dc.date.accessioned2022-11-18T05:08:23Z
dc.date.available2022-11-18T05:08:23Z
dc.date.issued2016-02-05
dc.identifier.citationHalliwell, Barry, Cheah, Irwin K, Drum, Chester L (2016-02-05). Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 470 (2) : 245-250. ScholarBank@NUS Repository. https://doi.org/10.1016/j.bbrc.2015.12.124
dc.identifier.issn0006291X
dc.identifier.issn10902104
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/234702
dc.description.abstractErgothioneine (ET) is a diet-derived, thiolated derivative of histidine with antioxidant properties. Although ET is produced only by certain fungi and bacteria, it can be found at high concentrations in certain human and animal tissues and is absorbed through a specific, high affinity transporter (OCTN1). In liver, heart, joint and intestinal injury, elevated ET concentrations have been observed in injured tissues. The physiological role of ET remains unclear. We thus review current literature to generate a specific hypothesis: that the accumulation of ET in vivo is an adaptive mechanism, involving the regulated uptake and concentration of an exogenous natural compound to minimize oxidative damage.
dc.language.isoen
dc.publisherACADEMIC PRESS INC ELSEVIER SCIENCE
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectBiochemistry & Molecular Biology
dc.subjectBiophysics
dc.subjectReactive oxygen species
dc.subjectAntioxidant
dc.subjectErgothioneine
dc.subjectAdaptation
dc.subjectOCTN1
dc.subjectMushrooms
dc.subjectORGANIC CATION TRANSPORTER
dc.subjectRED-BLOOD-CELLS
dc.subjectRHEUMATOID-ARTHRITIS
dc.subjectOXIDATIVE STRESS
dc.subjectCROHNS-DISEASE
dc.subjectAMINO-ACID
dc.subjectGENETIC-VARIATIONS
dc.subject503F VARIANT
dc.subjectSLC22A5 GENE
dc.subjectHIGH-FAT
dc.typeReview
dc.date.updated2022-11-18T02:38:39Z
dc.contributor.departmentBIOCHEMISTRY
dc.contributor.departmentMEDICINE
dc.description.doi10.1016/j.bbrc.2015.12.124
dc.description.sourcetitleBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
dc.description.volume470
dc.description.issue2
dc.description.page245-250
dc.published.statePublished
Appears in Collections:Staff Publications
Elements

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
1-s2.0-S0006291X15311281-main.pdf800.24 kBAdobe PDF

CLOSED

Published

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.