Please use this identifier to cite or link to this item: https://doi.org/10.1515/jpm-2020-0298
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dc.titleRisk factors for pregnancy-associated venous thromboembolism in Singapore
dc.contributor.authorJaya-Bodestyne, Sandra Lynn
dc.contributor.authorLee, Lai Heng
dc.contributor.authorTan, Lay Kok
dc.contributor.authorTan, Kok Hian
dc.contributor.authorØstbye, T.
dc.contributor.authorMalhotra, Rahul
dc.contributor.authorAllen, John
dc.contributor.authorTan, Sophie Seine Xuan
dc.contributor.authorTan, Melinda Si Yun
dc.contributor.authorNg, Lawrence Cheng Kiat
dc.contributor.authorYong, Yang
dc.contributor.authorTan, Thiam Chye
dc.date.accessioned2022-10-26T09:21:30Z
dc.date.available2022-10-26T09:21:30Z
dc.date.issued2020-09-05
dc.identifier.citationJaya-Bodestyne, Sandra Lynn, Lee, Lai Heng, Tan, Lay Kok, Tan, Kok Hian, Østbye, T., Malhotra, Rahul, Allen, John, Tan, Sophie Seine Xuan, Tan, Melinda Si Yun, Ng, Lawrence Cheng Kiat, Yong, Yang, Tan, Thiam Chye (2020-09-05). Risk factors for pregnancy-associated venous thromboembolism in Singapore. Journal of Perinatal Medicine 49 (2) : 153-158. ScholarBank@NUS Repository. https://doi.org/10.1515/jpm-2020-0298
dc.identifier.issn0300-5577
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/233871
dc.description.abstractPregnancy-associated venous thromboembolism (VTE), including deep venous thrombosis (DVT) and pulmonary embolism (PE), is associated with increased risk of maternal mortality and morbidity. This study aimed to assess potential risk factors for pregnancy-associated VTE. In this case-control study, women with pregnancy-associated VTE were identified via International Classification of Diseases codes and included if they had been objectively diagnosed with VTE during pregnancy or within six weeks postpartum, from 2004 to 2016, at KK Women's and Children's Hospital or Singapore General Hospital in Singapore. Controls, i.e. pregnant women without VTE, were selected from a prospective longitudinal study. The odds ratio (OR) for VTE was computed for a range of maternal and obstetric factors. From 2004 to 2016, 89 cases of pregnancy-associated VTE and 926 controls were identifed and analysed using logistic regression. The most significant risk factors for pregnancy-associated VTE were smoking (OR 5.44, p=0.0002) and preterm delivery (OR 5.06, p=0.023). Malay race, multiparity, non-O blood group and caesarean section, were also identified to be of higher risk. These risk factors should be useful in the development of thromboprophylaxis strategies for pregnancy and the postpartum period, especially in Singapore. © 2020 Sandra Lynn Jaya-Bodestyne et al., published by De Gruyter, Berlin/Boston.
dc.publisherDe Gruyter Open Ltd
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScopus OA2021
dc.subjectpostpartum
dc.subjectpregnancy
dc.subjectrisk factors
dc.subjectvenous thromboembolism
dc.typeArticle
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.description.doi10.1515/jpm-2020-0298
dc.description.sourcetitleJournal of Perinatal Medicine
dc.description.volume49
dc.description.issue2
dc.description.page153-158
dc.published.statePublished
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