Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.jgar.2020.11.025
DC Field | Value | |
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dc.title | A point prevalence survey to assess antibiotic prescribing in patients hospitalized with confirmed and suspected coronavirus disease 2019 (COVID-19) | |
dc.contributor.author | Tan, Sock Hoon | |
dc.contributor.author | Ng, Tat Ming | |
dc.contributor.author | Tay, Hui Lin | |
dc.contributor.author | Yap, Min Yi | |
dc.contributor.author | Heng, Shi Thong | |
dc.contributor.author | Loo, Audrey Yong Xin | |
dc.contributor.author | Teng, Christine B. | |
dc.contributor.author | Lee, Tau Hong | |
dc.date.accessioned | 2022-10-13T01:14:00Z | |
dc.date.available | 2022-10-13T01:14:00Z | |
dc.date.issued | 2021-03-01 | |
dc.identifier.citation | Tan, Sock Hoon, Ng, Tat Ming, Tay, Hui Lin, Yap, Min Yi, Heng, Shi Thong, Loo, Audrey Yong Xin, Teng, Christine B., Lee, Tau Hong (2021-03-01). A point prevalence survey to assess antibiotic prescribing in patients hospitalized with confirmed and suspected coronavirus disease 2019 (COVID-19). Journal of Global Antimicrobial Resistance 24 : 45-47. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jgar.2020.11.025 | |
dc.identifier.issn | 2213-7165 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/232834 | |
dc.description.abstract | Background: Earlier studies have reported high antibiotic use in patients hospitalised for coronavirus disease 2019 (COVID-19), resulting in concerns of increasing antimicrobial resistance with increase antibiotic use in this pandemic. Point prevalence survey (PPS) can be a quick tool to provide antibiotic prescribing information to aid antimicrobial stewardship (AMS) activities. Objectives: To describe antibiotic utilization and evaluate antibiotic appropriateness in COVID-19 patients using PPS. Methods: Adapting Global-PPS on antimicrobial use, the survey was conducted in COVID-19 wards at 2 centres in Singapore on 22 April 2020 at 0800h. Patients on systemic antibiotics were included and evaluated for antibiotic appropriateness. Results: Five hundred and seventy-seven patients were screened. Thirty-six (6.2%) patients were on antibiotics and which were started at median of 7 days (inter-quartile rate (IQR), 4, 11) from symptom onset. Fifty-one antibiotics were prescribed in these patients. Overall, co-amoxiclav (26/51, 51.0%) was the most often prescribed antibiotic. Thirty-one out of 51 (60.8%) antibiotic prescriptions were appropriate. Among 20 inappropriate prescriptions, 18 (90.0%) were initiated in patients with low likelihood of bacterial infections. Antibiotic prescriptions were more appropriate when reviewed by infectious diseases physicians (13/31 [41.9%] versus 2/20 [10.0%], p = 0.015), and if reasons for use were stated in notes (31/31 [100.0%] versus 16/20 [80.0%], p = 0.019). Conclusions: Despite low prevalence of antibiotic use among confirmed and suspected COVID-19 patients at 2 centres in Singapore, there was significant proportion of inappropriate antibiotics use where bacterial infections were unlikely. AMS teams can tailor stewardship strategies using PPS results. © 2020 The Author(s) | |
dc.publisher | Elsevier Ltd | |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Scopus OA2021 | |
dc.subject | Antibiotic | |
dc.subject | Coronavirus | |
dc.subject | COVID-19 | |
dc.subject | Point prevalence survey | |
dc.subject | Stewardship | |
dc.type | Article | |
dc.contributor.department | PHARMACY | |
dc.description.doi | 10.1016/j.jgar.2020.11.025 | |
dc.description.sourcetitle | Journal of Global Antimicrobial Resistance | |
dc.description.volume | 24 | |
dc.description.page | 45-47 | |
Appears in Collections: | Elements Staff Publications |
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