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Please use this identifier to cite or link to this item: https://doi.org/10.2196/22219
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dc.titleWhat every reader should know about studies using electronic health record data but may be afraid to ask
dc.contributor.authorKohane, Isaac S.
dc.contributor.authorAronow, Bruce J.
dc.contributor.authorAvillach, Paul
dc.contributor.authorBeaulieu-Jones, Brett K.
dc.contributor.authorBellazzi, Riccardo
dc.contributor.authorBradford, Robert L.
dc.contributor.authorBrat, Gabriel A.
dc.contributor.authorCannataro, Mario
dc.contributor.authorCimino, James J.
dc.contributor.authorGarcía-Barrio, N.
dc.contributor.authorGehlenborg, Nils
dc.contributor.authorGhassemi, Marzyeh
dc.contributor.authorGutiérrez-Sacristán, A.
dc.contributor.authorHanauer, David A.
dc.contributor.authorHolmes, John H.
dc.contributor.authorHong, Chuan
dc.contributor.authorKlann, Jeffrey G.
dc.contributor.authorLoh, Ne Hooi Will
dc.contributor.authorLuo, Yuan
dc.contributor.authorMandl, Kenneth D.
dc.contributor.authorDaniar, Mohamad
dc.contributor.authorMoore, Jason H.
dc.contributor.authorMurphy, Shawn N.
dc.contributor.authorNeuraz, Antoine
dc.contributor.authorNgiam, Kee Yuan
dc.contributor.authorOmenn, Gilbert S.
dc.contributor.authorPalmer, Nathan
dc.contributor.authorPatel, Lav P.
dc.contributor.authorPedrera-Jiménez, M.
dc.contributor.authorSliz, Piotr
dc.contributor.authorSouth, Andrew M.
dc.contributor.authorTan, Amelia Li Min
dc.contributor.authorTaylor, Deanne M.
dc.contributor.authorTaylor, Bradley W.
dc.contributor.authorTorti, Carlo
dc.contributor.authorVallejos, Andrew K.
dc.contributor.authorWagholikar, Kavishwar B.
dc.contributor.authorWeber, Griffin M.
dc.contributor.authorCai, Tianxi
dc.contributor.authorAlbayrak, A.
dc.contributor.authorAmendola, D.F.
dc.contributor.authorAnthony, L.L.L.J.
dc.contributor.authorAtz, A.
dc.contributor.authorBell, D.S.
dc.contributor.authorBellasi, A.
dc.contributor.authorBenoit, V.
dc.contributor.authorBeraghi, M.
dc.contributor.authorSobrino, J.L.B.
dc.contributor.authorBernaux, M.
dc.contributor.authorBey, R.
dc.contributor.authorMartínez, A.B.
dc.contributor.authorBoeker, M.
dc.contributor.authorBonzel, C.-L.
dc.contributor.authorBooth, J.
dc.contributor.authorBosari, S.
dc.contributor.authorBourgeois, F.T.
dc.contributor.authorBréant, S.
dc.contributor.authorBucalo, M.
dc.contributor.authorBurgun, A.
dc.contributor.authorCao, A.
dc.contributor.authorCaucheteux, C.
dc.contributor.authorChamp, J.
dc.contributor.authorChiovato, L.
dc.contributor.authorColicchio, T.K.
dc.contributor.authorCormont, S.
dc.contributor.authorCossin, S.
dc.contributor.authorCraig, J.
dc.contributor.authorBermúdez, J.L.C.
dc.contributor.authorDagliati, A.
dc.contributor.authorDaniel, C.
dc.contributor.authorDavoudi, A.
dc.contributor.authorDevkota, B.
dc.contributor.authorDubiel, J.
dc.contributor.authorDuVall, S.L.
dc.contributor.authorEsteve, L.
dc.contributor.authorFan, S.
dc.contributor.authorFollett, R.W.
dc.contributor.authorGaiolla, P.S.A.
dc.contributor.authorGanslandt, T.
dc.contributor.authorBarrio, N.G.
dc.contributor.authorGeva, A.
dc.contributor.authorGradinger, T.
dc.contributor.authorGramfort, A.
dc.contributor.authorGriffier, R.
dc.contributor.authorGriffon, N.
dc.contributor.authorGrisel, O.
dc.contributor.authorHaverkamp, C.
dc.contributor.authorHilka, M.
dc.contributor.authorHorki, P.
dc.contributor.authorHutch, M.R.
dc.contributor.authorIssitt, R.
dc.contributor.authorJannot, A.S.
dc.contributor.authorJouhet, V.
dc.contributor.authorKeller, M.S.
dc.contributor.authorKirchoff, K.
dc.contributor.authorKrantz, I.D.
dc.contributor.authorKraska, D.
dc.contributor.authorKrishnamurthy, A.K.
dc.contributor.authorL'Yi, S.
dc.contributor.authorLe, T.T.
dc.contributor.authorLeblanc, J.
dc.contributor.authorLemaitre, G.
dc.contributor.authorLenert, L.
dc.contributor.authorLeprovost, D.
dc.contributor.authorLiu, M.
dc.contributor.authorLynch, K.E.
dc.contributor.authorMahmood, S.
dc.contributor.authorMaidlow, S.
dc.contributor.authorMalovini, A.
dc.contributor.authorMao, C.
dc.contributor.authorMartel, P.
dc.contributor.authorMasino, A.J.
dc.contributor.authorMatheny, M.E.
dc.contributor.authorMaulhardt, T.
dc.contributor.authorMcDuffie, M.T.
dc.contributor.authorMensch, A.
dc.contributor.authorMinicucci, M.F.
dc.contributor.authorMoal, B.
dc.contributor.authorMorris, J.S.
dc.contributor.authorMorris, M.
dc.contributor.authorMoshal, K.L.
dc.contributor.authorMousavi, S.
dc.contributor.authorMowery, D.L.
dc.contributor.authorMurad, D.A.
dc.contributor.authorObeid, J.
dc.contributor.authorOkoshi, M.P.
dc.contributor.authorOlson, K.L.
dc.contributor.authorOrlova, N.
dc.contributor.authorOstasiewski, B.D.
dc.contributor.authorParis, N.
dc.contributor.authorJimenez, M.P.
dc.contributor.authorProkosch, H.U.
dc.contributor.authorPrudente, R.A.
dc.contributor.authorRamoni, R.B.
dc.contributor.authorRaskin, M.
dc.contributor.authorRieg, S.
dc.contributor.authorDomínguez, G.R.
dc.contributor.authorSalamanca, E.
dc.contributor.authorSamayamuthu, M.J.
dc.contributor.authorSandrin, A.
dc.contributor.authorSchiver, E.
dc.contributor.authorSchuettler, J.
dc.contributor.authorScudeller, L.
dc.contributor.authorSebire, N.
dc.contributor.authorBalazote, P.S.
dc.contributor.authorSerre, P.
dc.contributor.authorSerret-Larmande, A.
dc.contributor.authorSilvio, D.
dc.contributor.authorSon, J.
dc.contributor.authorSpiridou, A.
dc.contributor.authorTan, B.W.Q.
dc.contributor.authorTan, B.W.L.
dc.contributor.authorTanni, S.E.
dc.contributor.authorTibollo, V.
dc.contributor.authorTippmann, P.
dc.contributor.authorVaroquaux, G.
dc.contributor.authorVie, J.-J.
dc.contributor.authorVisweswaran, S.
dc.contributor.authorWaitman, L.R.
dc.contributor.authorWassermann, D.
dc.contributor.authorWilliam, Y.
dc.contributor.authorXia, Z.
dc.contributor.authorZambelli, A.
dc.contributor.authorCarmona, A.
dc.contributor.authorSonday, C.
dc.contributor.authorBalshi, J.
dc.contributor.authorThe Consortium For Clinical Characterization Of COVID-19 By EHR (4CE).
dc.date.accessioned2022-10-11T08:01:56Z
dc.date.available2022-10-11T08:01:56Z
dc.date.issued2021-03-02
dc.identifier.citationKohane, Isaac S., Aronow, Bruce J., Avillach, Paul, Beaulieu-Jones, Brett K., Bellazzi, Riccardo, Bradford, Robert L., Brat, Gabriel A., Cannataro, Mario, Cimino, James J., García-Barrio, N., Gehlenborg, Nils, Ghassemi, Marzyeh, Gutiérrez-Sacristán, A., Hanauer, David A., Holmes, John H., Hong, Chuan, Klann, Jeffrey G., Loh, Ne Hooi Will, Luo, Yuan, Mandl, Kenneth D., Daniar, Mohamad, Moore, Jason H., Murphy, Shawn N., Neuraz, Antoine, Ngiam, Kee Yuan, Omenn, Gilbert S., Palmer, Nathan, Patel, Lav P., Pedrera-Jiménez, M., Sliz, Piotr, South, Andrew M., Tan, Amelia Li Min, Taylor, Deanne M., Taylor, Bradley W., Torti, Carlo, Vallejos, Andrew K., Wagholikar, Kavishwar B., Weber, Griffin M., Cai, Tianxi, Albayrak, A., Amendola, D.F., Anthony, L.L.L.J., Atz, A., Bell, D.S., Bellasi, A., Benoit, V., Beraghi, M., Sobrino, J.L.B., Bernaux, M., Bey, R., Martínez, A.B., Boeker, M., Bonzel, C.-L., Booth, J., Bosari, S., Bourgeois, F.T., Bréant, S., Bucalo, M., Burgun, A., Cao, A., Caucheteux, C., Champ, J., Chiovato, L., Colicchio, T.K., Cormont, S., Cossin, S., Craig, J., Bermúdez, J.L.C., Dagliati, A., Daniel, C., Davoudi, A., Devkota, B., Dubiel, J., DuVall, S.L., Esteve, L., Fan, S., Follett, R.W., Gaiolla, P.S.A., Ganslandt, T., Barrio, N.G., Geva, A., Gradinger, T., Gramfort, A., Griffier, R., Griffon, N., Grisel, O., Haverkamp, C., Hilka, M., Horki, P., Hutch, M.R., Issitt, R., Jannot, A.S., Jouhet, V., Keller, M.S., Kirchoff, K., Krantz, I.D., Kraska, D., Krishnamurthy, A.K., L'Yi, S., Le, T.T., Leblanc, J., Lemaitre, G., Lenert, L., Leprovost, D., Liu, M., Lynch, K.E., Mahmood, S., Maidlow, S., Malovini, A., Mao, C., Martel, P., Masino, A.J., Matheny, M.E., Maulhardt, T., McDuffie, M.T., Mensch, A., Minicucci, M.F., Moal, B., Morris, J.S., Morris, M., Moshal, K.L., Mousavi, S., Mowery, D.L., Murad, D.A., Obeid, J., Okoshi, M.P., Olson, K.L., Orlova, N., Ostasiewski, B.D., Paris, N., Jimenez, M.P., Prokosch, H.U., Prudente, R.A., Ramoni, R.B., Raskin, M., Rieg, S., Domínguez, G.R., Salamanca, E., Samayamuthu, M.J., Sandrin, A., Schiver, E., Schuettler, J., Scudeller, L., Sebire, N., Balazote, P.S., Serre, P., Serret-Larmande, A., Silvio, D., Son, J., Spiridou, A., Tan, B.W.Q., Tan, B.W.L., Tanni, S.E., Tibollo, V., Tippmann, P., Varoquaux, G., Vie, J.-J., Visweswaran, S., Waitman, L.R., Wassermann, D., William, Y., Xia, Z., Zambelli, A., Carmona, A., Sonday, C., Balshi, J., The Consortium For Clinical Characterization Of COVID-19 By EHR (4CE). (2021-03-02). What every reader should know about studies using electronic health record data but may be afraid to ask. Journal of Medical Internet Research 23 (3) : e22219. ScholarBank@NUS Repository. https://doi.org/10.2196/22219
dc.identifier.issn1438-8871
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/232128
dc.description.abstractCoincident with the tsunami of COVID-19-related publications, there has been a surge of studies using real-world data, including those obtained from the electronic health record (EHR). Unfortunately, several of these high-profile publications were retracted because of concerns regarding the soundness and quality of the studies and the EHR data they purported to analyze. These retractions highlight that although a small community of EHR informatics experts can readily identify strengths and flaws in EHR-derived studies, many medical editorial teams and otherwise sophisticated medical readers lack the framework to fully critically appraise these studies. In addition, conventional statistical analyses cannot overcome the need for an understanding of the opportunities and limitations of EHR-derived studies. We distill here from the broader informatics literature six key considerations that are crucial for appraising studies utilizing EHR data: Data completeness, data collection and handling (eg, transformation), data type (ie, codified, textual), robustness of methods against EHR variability (within and across institutions, countries, and time), transparency of data and analytic code, and the multidisciplinary approach. These considerations will inform researchers, clinicians, and other stakeholders as to the recommended best practices in reviewing manuscripts, grants, and other outputs from EHR-data derived studies, and thereby promote and foster rigor, quality, and reliability of this rapidly growing field. © 2021 Journal of Medical Internet Research. All rights reserved.
dc.publisherJMIR Publications Inc.
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceScopus OA2021
dc.subjectCOVID-19
dc.subjectData quality
dc.subjectElectronic health records
dc.subjectLiterature
dc.subjectPublishing
dc.subjectQuality
dc.subjectReal-world data
dc.subjectReporting checklist
dc.subjectReporting standards
dc.subjectReview
dc.subjectStatistics
dc.typeReview
dc.contributor.departmentDEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
dc.description.doi10.2196/22219
dc.description.sourcetitleJournal of Medical Internet Research
dc.description.volume23
dc.description.issue3
dc.description.pagee22219
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