Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.vaccine.2020.06.007
DC FieldValue
dc.titleCOVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies? Comment
dc.contributor.authorSchaefer, G Owen
dc.contributor.authorTam, Clarence C
dc.contributor.authorSavulescu, Julian
dc.contributor.authorVoo, Teck Chuan
dc.date.accessioned2022-07-12T06:22:24Z
dc.date.available2022-07-12T06:22:24Z
dc.date.issued2020-07-14
dc.identifier.citationSchaefer, G Owen, Tam, Clarence C, Savulescu, Julian, Voo, Teck Chuan (2020-07-14). COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies? Comment. VACCINE 38 (33) : 5085-5088. ScholarBank@NUS Repository. https://doi.org/10.1016/j.vaccine.2020.06.007
dc.identifier.issn0264410X
dc.identifier.issn18732518
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/228280
dc.description.abstractWhile a human challenge study holds the prospect of accelerating the development of a vaccine for the coronavirus SARS-CoV-2, it may be opposed due to risks of harm to participants and researchers. Given the increasing number of human deaths and severe disruption to lives worldwide, we argue that a SARS-CoV-2 challenge study is ethically justifiable as its social value substantially outweighs the risks. Such a study should therefore be seriously considered as part of the global research response towards the COVID-19 pandemic. In this paper, we contribute to the debate by addressing the misperception that a challenge study for the coronavirus would lower scientific and ethical standards for vaccine research and development, and examine how it could be ethically conducted. We also set out information that needs to be disclosed to prospective participants to obtain their consent.
dc.language.isoen
dc.publisherELSEVIER SCI LTD
dc.sourceElements
dc.subjectScience & Technology
dc.subjectLife Sciences & Biomedicine
dc.subjectImmunology
dc.subjectMedicine, Research & Experimental
dc.subjectResearch & Experimental Medicine
dc.subjectCovid-19
dc.subjectCoronavirus
dc.subjectPandemic
dc.subjectHuman challenge study
dc.subjectEthics
dc.subjectVaccine
dc.typeEditorial
dc.date.updated2022-07-06T06:11:52Z
dc.contributor.departmentDEAN'S OFFICE (MEDICINE)
dc.contributor.departmentSAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
dc.description.doi10.1016/j.vaccine.2020.06.007
dc.description.sourcetitleVACCINE
dc.description.volume38
dc.description.issue33
dc.description.page5085-5088
dc.published.statePublished
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