Please use this identifier to cite or link to this item: https://doi.org/10.1109/ACCESS.2019.2924827
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dc.titleOptimized Code Design for Constrained DNA Data Storage With Asymmetric Errors
dc.contributor.authorDeng, L.
dc.contributor.authorWang, Y.
dc.contributor.authorNoor-A-Rahim, M.D.
dc.contributor.authorGuan, Y.L.
dc.contributor.authorShi, Z.
dc.contributor.authorGunawan, E.
dc.contributor.authorPoh, C.L.
dc.date.accessioned2021-12-29T04:39:10Z
dc.date.available2021-12-29T04:39:10Z
dc.date.issued2019
dc.identifier.citationDeng, L., Wang, Y., Noor-A-Rahim, M.D., Guan, Y.L., Shi, Z., Gunawan, E., Poh, C.L. (2019). Optimized Code Design for Constrained DNA Data Storage With Asymmetric Errors. IEEE Access 7 : 84107-84121. ScholarBank@NUS Repository. https://doi.org/10.1109/ACCESS.2019.2924827
dc.identifier.issn21693536
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/212361
dc.description.abstractWith ultra-high density and preservation longevity, deoxyribonucleic acid (DNA)-based data storage is becoming an emerging storage technology. Limited by the current biochemical techniques, data might be corrupted during the processes of DNA data storage. A hybrid coding architecture consisting of modified variable-length run-length limited (VL-RLL) codes and optimized protograph low-density parity-check (LDPC) codes is proposed in order to suppress error occurrence and correct asymmetric substitution errors. Based on the analyses of the different asymmetric DNA sequencer channel models, a series of the protograph LDPC codes are optimized using a modified extrinsic information transfer algorithm (EXIT). The simulation results show the better error performance of the proposed protograph LDPC codes over the conventional good codes and the codes used in the existing DNA data storage system. In addition, the theoretical analysis shows that the proposed hybrid coding scheme stores 1.98 bits per nucleotide (bits/nt) with only 1% gap from the upper boundary (2 bits/nt). © 2013 IEEE.
dc.publisherInstitute of Electrical and Electronics Engineers Inc.
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceScopus OA2019
dc.subjectasymmetric substitutions
dc.subjectconstrained codes
dc.subjectDNA data storage
dc.subjectDNA sequencing
dc.subjectprotograph LDPC codes
dc.typeArticle
dc.contributor.departmentDEPT OF BIOMEDICAL ENGINEERING
dc.description.doi10.1109/ACCESS.2019.2924827
dc.description.sourcetitleIEEE Access
dc.description.volume7
dc.description.page84107-84121
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