Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0213615
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dc.titleFactors associated with false-positive mammography at first screen in an Asian population
dc.contributor.authorHo, Peh Joo
dc.contributor.authorBok, Chek Mei
dc.contributor.authorIshak, Hanis Mariyah Mohd
dc.contributor.authorLim, Li Yan
dc.contributor.authorLiu, Jenny
dc.contributor.authorWong, Fuh Yong
dc.contributor.authorChia, Kee Seng
dc.contributor.authorTan, Min-Han
dc.contributor.authorChay, Wen Yee
dc.contributor.authorHartman, Mikael
dc.contributor.authorLi, Jingmei
dc.date.accessioned2021-11-26T04:04:55Z
dc.date.available2021-11-26T04:04:55Z
dc.date.issued2019-03-11
dc.identifier.citationHo, Peh Joo, Bok, Chek Mei, Ishak, Hanis Mariyah Mohd, Lim, Li Yan, Liu, Jenny, Wong, Fuh Yong, Chia, Kee Seng, Tan, Min-Han, Chay, Wen Yee, Hartman, Mikael, Li, Jingmei (2019-03-11). Factors associated with false-positive mammography at first screen in an Asian population. PLOS ONE 14 (3). ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0213615
dc.identifier.issn19326203
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/208268
dc.description.abstractIntroduction False-positive recall is an issue in national screening programmes. The aim of this study is to investigate the recall rate at first screen and to identify potential predictors of false-positive recall in a multi-ethnic Asian population-based breast cancer screening programme. Methods Women aged 50–64 years attending screening mammography for the first time (n = 25,318) were included in this study. The associations between potential predictors (sociodemo-graphic, lifestyle and reproductive) and false-positive recall were evaluated using multivariable logistic regression models. Results The recall rate was 7.6% (n = 1,923), of which with 93.8% were false-positive. Factors independently associated with higher false-positive recall included Indian ethnicity (odds ratio [95% confidence interval]: 1.52 [1.25 to 1.84]), premenopause (1.23 [1.04 to 1.44]), nulliparity (1.85 [1.57 to 2.17]), recent breast symptoms (1.72 [1.31 to 2.23]) and history of breast lump excision (1.87 [1.53 to 2.26]). Factors associated with lower risk of false-positive recall included older age at screen (0.84 [0.73 to 0.97]) and use of oral contraceptives (0.87 [0.78 to 0.97]). After further adjustment of percent mammographic density, associations with older age at screening (0.97 [0.84 to 1.11]) and menopausal status (1.12 [0.95 to 1.32]) were attenuated and no longer significant. Conclusion For every breast cancer identified, 15 women without cancer were subjected to further testing. Efforts to educate Asian women on what it means to be recalled will be useful in reducing unnecessary stress and anxiety.
dc.language.isoen
dc.publisherPUBLIC LIBRARY SCIENCE
dc.sourceElements
dc.subjectScience & Technology
dc.subjectMultidisciplinary Sciences
dc.subjectScience & Technology - Other Topics
dc.subjectHORMONE REPLACEMENT THERAPY
dc.subjectBREAST-CANCER
dc.subjectDIGITAL MAMMOGRAPHY
dc.subjectPSYCHOSOCIAL CONSEQUENCES
dc.subjectRE-ATTENDANCE
dc.subjectRECALL RATE
dc.subjectWOMEN
dc.subjectRISK
dc.subjectPREVALENCE
dc.subjectPREDICTORS
dc.typeArticle
dc.date.updated2021-11-25T16:25:08Z
dc.contributor.departmentDEPT OF SURGERY
dc.contributor.departmentDUKE-NUS MEDICAL SCHOOL
dc.contributor.departmentEPIDEMIOLOGY & PUBLIC HEALTH
dc.contributor.departmentSAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
dc.description.doi10.1371/journal.pone.0213615
dc.description.sourcetitlePLOS ONE
dc.description.volume14
dc.description.issue3
dc.published.statePublished
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