Please use this identifier to cite or link to this item: https://doi.org/10.1002/9781118307816.ch42
DC FieldValue
dc.titleEvidence of Hormonal, Laboratory, Biochemical, and Instrumental Diagnostics of Endocrine Tumors of the Pancreas
dc.contributor.authorNg, DCE
dc.contributor.authorMukherjee, JJ
dc.contributor.authorLee, KO
dc.date.accessioned2021-11-12T06:42:02Z
dc.date.available2021-11-12T06:42:02Z
dc.date.issued2015-04-07
dc.identifier.citationNg, DCE, Mukherjee, JJ, Lee, KO (2015-04-07). Evidence of Hormonal, Laboratory, Biochemical, and Instrumental Diagnostics of Endocrine Tumors of the Pancreas. Pancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management : 301-309. ScholarBank@NUS Repository. https://doi.org/10.1002/9781118307816.ch42
dc.identifier.isbn9780470673188
dc.identifier.urihttps://scholarbank.nus.edu.sg/handle/10635/206061
dc.description.abstractPancreatic endocrine tumors secrete inappropriately high levels of specific endocrine hormones, as well as peptides such as chromogranin A, pancreatic polypeptide, and synaptophysin. Strict conditions of measurement are necessary as these hormones and peptides are proteolyzed rapidly, may be secreted episodically, and are affected by commonly used drugs. Tumors may secrete variants of the hormone not measureable by commercially available assays. In patients with multiple endocrine neoplasia syndrome type 1 (MEN-1), gene sequencing is not recommended at the moment, but it may eventually be useful. Asymptomatic patients require monitoring for pancreatic endocrine tumors by regular screening of hormones. After biochemical confirmation of the diagnosis, localization may be difficult in some small tumors. Conventional imaging techniques are useful but, as these tumors express cell-surface somatostatin receptors (SSTRs), advances in the use of specialized SSTR-linked radionuclide scanning have improved their localization greatly. However, these are expensive and may not be generally available.
dc.publisherJohn Wiley & Sons, Ltd
dc.sourceElements
dc.typeBook Chapter
dc.date.updated2021-11-10T06:55:21Z
dc.contributor.departmentMEDICINE
dc.description.doi10.1002/9781118307816.ch42
dc.description.sourcetitlePancreatic Cancer, Cystic Neoplasms and Endocrine Tumors: Diagnosis and Management
dc.description.page301-309
dc.published.statePublished
Appears in Collections:Staff Publications
Elements

Show simple item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
LeeBeger_3188_c42_main-Ng%2c%20JJ%2c%20Lee-JJ%20comments.pdfAccepted version2.85 MBAdobe PDF

CLOSED

Post-print

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.