Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/201169
DC Field | Value | |
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dc.title | Semaphorin Signaling in Cardiovascular Development | |
dc.contributor.author | Epstein, Jonathan A | |
dc.contributor.author | Aghajanian, Haig | |
dc.contributor.author | Singh, Manvendra K | |
dc.date.accessioned | 2021-09-27T08:36:57Z | |
dc.date.available | 2021-09-27T08:36:57Z | |
dc.date.issued | 2015-02-03 | |
dc.identifier.citation | Epstein, Jonathan A, Aghajanian, Haig, Singh, Manvendra K (2015-02-03). Semaphorin Signaling in Cardiovascular Development. CELL METABOLISM 21 (2) : 163-173. ScholarBank@NUS Repository. | |
dc.identifier.issn | 15504131 | |
dc.identifier.issn | 19327420 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/201169 | |
dc.description.abstract | Semaphorins were originally identified as neuronal guidance molecules mediating their attractive or repulsive signals by forming complexes with plexin and neuropilin receptors. Subsequent research has identified functions for semaphorin signaling in many organs and tissues outside of the nervous system. Vital roles for semaphorin signaling in vascular patterning and cardiac morphogenesis have been demonstrated, and impaired semaphorin signaling has been associated with various human cardiovascular disorders, including persistent truncus arteriosus, sinus bradycardia and anomalous pulmonary venous connections. Here, we review the functions of semaphorins and their receptors in cardiovascular development and disease and highlight important recent discoveries in the field. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.cmet.2014.12.015 | |
dc.language.iso | en | |
dc.publisher | CELL PRESS | |
dc.source | Elements | |
dc.subject | Science & Technology | |
dc.subject | Life Sciences & Biomedicine | |
dc.subject | Cell Biology | |
dc.subject | Endocrinology & Metabolism | |
dc.subject | CARDIAC NEURAL CREST | |
dc.subject | ENDOTHELIAL GROWTH-FACTOR | |
dc.subject | VENTRICULAR MYOCARDIUM | |
dc.subject | IN-VIVO | |
dc.subject | ISOLATED NONCOMPACTION | |
dc.subject | INDUCED ANGIOGENESIS | |
dc.subject | TRUNCUS ARTERIOSUS | |
dc.subject | TUMOR ANGIOGENESIS | |
dc.subject | CONDUCTION SYSTEM | |
dc.subject | MULTIFACETED ROLE | |
dc.type | Review | |
dc.date.updated | 2021-09-22T02:29:50Z | |
dc.contributor.department | DUKE-NUS MEDICAL SCHOOL | |
dc.description.sourcetitle | CELL METABOLISM | |
dc.description.volume | 21 | |
dc.description.issue | 2 | |
dc.description.page | 163-173 | |
dc.identifier.isiut | 000349381400006 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
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