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https://doi.org/10.1038/s41598-020-76105-2
DC Field | Value | |
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dc.title | A prospective observational prevalence study of elevated HbA1c among elective surgical patients | |
dc.contributor.author | Teo, L.M. | |
dc.contributor.author | Lim, W.Y. | |
dc.contributor.author | Ke, Y. | |
dc.contributor.author | Sia, I.K.L. | |
dc.contributor.author | Gui, C.H. | |
dc.contributor.author | Abdullah, H.R. | |
dc.date.accessioned | 2021-08-25T14:05:24Z | |
dc.date.available | 2021-08-25T14:05:24Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Teo, L.M., Lim, W.Y., Ke, Y., Sia, I.K.L., Gui, C.H., Abdullah, H.R. (2020). A prospective observational prevalence study of elevated HbA1c among elective surgical patients. Scientific Reports 10 (1) : 19067. ScholarBank@NUS Repository. https://doi.org/10.1038/s41598-020-76105-2 | |
dc.identifier.issn | 20452322 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/199296 | |
dc.description.abstract | Type 2 Diabetes Mellitus (DM) is a chronic disease with high prevalence worldwide. Using glycated haemoglobin (HbA1c) as a surrogate for potential pre-DM and DM conditions, our primary objective was to determine the HbA1c epidemiology in non-cardiac elective surgical patients in Singapore. Our secondary aim was to identify risk factors associated with elevated HbA1c. We conducted a prospective, observational single-centre study in adult patients. HbA1c screening was performed. Patient demographics and comorbidities were recorded. Patients were divided into those with HbA1C ? 6.0% and HbA1C ? 6.1%. Regression analyses were performed to identify associated factors. Subgroup analysis was performed comparing patients with HbA1C ? 6.1% and HbA1C ? 8.0%. Of the 875 patients recruited, 182 (20.8%) had HbA1c ? 6.1%, of which 32 (3.7%) had HbA1c ? 8%. HbA1C ? 6.1% was associated with Indian ethnicity [1.07 (1.01–1.13), p = 0.023], BMI > 27.5 [1.07 (1.02–1.11), p = 0.002], higher preoperative random serum glucose [1.03 (1.02–1.04), p < 0.001], pre-existing diagnosis of DM [1.85 (1.75–1.96), p < 0.001] and prediabetes [1.44 (1.24–1.67), p < 0.001], and peripheral vascular disease [1.30 (1.10–1.54), p = 0.002]. HbA1c ? 8% had an additional association with age > 60 years [0.96 (0.93–0.99), p = 0.017]. The prevalence of elevated HbA1c is high among the surgical population. Targeted preoperative HbA1c screening for at-risk elective surgical patients reduces cost, allowing focused use of healthcare resources. © 2020, The Author(s). | |
dc.publisher | Nature Research | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.source | Scopus OA2020 | |
dc.type | Article | |
dc.contributor.department | DUKE-NUS MEDICAL SCHOOL | |
dc.description.doi | 10.1038/s41598-020-76105-2 | |
dc.description.sourcetitle | Scientific Reports | |
dc.description.volume | 10 | |
dc.description.issue | 1 | |
dc.description.page | 19067 | |
Appears in Collections: | Staff Publications Elements |
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