Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.jns.2019.116628
DC Field | Value | |
---|---|---|
dc.title | The prognostic utility of ICH-score in anticoagulant related intracerebral hemorrhage | |
dc.contributor.author | Katsanos, Aristeidis H | |
dc.contributor.author | Krogias, Christos | |
dc.contributor.author | Lioutas, Vasileios-Arsenios | |
dc.contributor.author | Goyal, Nitin | |
dc.contributor.author | Zand, Ramin | |
dc.contributor.author | Sharma, Vijay K | |
dc.contributor.author | Varelas, Panayiotis | |
dc.contributor.author | Malhotra, Konark | |
dc.contributor.author | Paciaroni, Maurizio | |
dc.contributor.author | Sharaf, Aboubakar | |
dc.contributor.author | Chang, Jason | |
dc.contributor.author | Karapanayiotides, Theodore | |
dc.contributor.author | Kargiotis, Odysseas | |
dc.contributor.author | Pappa, Alexandra | |
dc.contributor.author | Mai, Jeffrey | |
dc.contributor.author | Tsantes, Argyrios | |
dc.contributor.author | Boviatsis, Efstathios | |
dc.contributor.author | Lambadiari, Vaia | |
dc.contributor.author | Shoamanesh, Ashkan | |
dc.contributor.author | Mitsias, Panayiotis D | |
dc.contributor.author | Selim, Magdy H | |
dc.contributor.author | Alexandrov, Andrei V | |
dc.contributor.author | Tsivgoulis, Georgios | |
dc.date.accessioned | 2021-07-01T00:52:48Z | |
dc.date.available | 2021-07-01T00:52:48Z | |
dc.date.issued | 2020-02-15 | |
dc.identifier.citation | Katsanos, Aristeidis H, Krogias, Christos, Lioutas, Vasileios-Arsenios, Goyal, Nitin, Zand, Ramin, Sharma, Vijay K, Varelas, Panayiotis, Malhotra, Konark, Paciaroni, Maurizio, Sharaf, Aboubakar, Chang, Jason, Karapanayiotides, Theodore, Kargiotis, Odysseas, Pappa, Alexandra, Mai, Jeffrey, Tsantes, Argyrios, Boviatsis, Efstathios, Lambadiari, Vaia, Shoamanesh, Ashkan, Mitsias, Panayiotis D, Selim, Magdy H, Alexandrov, Andrei V, Tsivgoulis, Georgios (2020-02-15). The prognostic utility of ICH-score in anticoagulant related intracerebral hemorrhage. JOURNAL OF THE NEUROLOGICAL SCIENCES 409. ScholarBank@NUS Repository. https://doi.org/10.1016/j.jns.2019.116628 | |
dc.identifier.issn | 0022510X | |
dc.identifier.issn | 18785883 | |
dc.identifier.uri | https://scholarbank.nus.edu.sg/handle/10635/192663 | |
dc.description.abstract | Although intracerebral hemorrhage (ICH) score is used to provide an estimate on the probability of mortality following spontaneous ICH of any cause, its utility has not been exclusively tested in ICH patients with history of treatment with vitamin K antagonists (VKAs) or non-vitamin K oral anticoagulants (NOACs). The aim of the present report is to investigate the utility of ICH score for mortality prognostication of VKA-ICH and NOAC-ICH patients. We used receiver operating characteristic curve analyses to estimate the accuracy parameters for the different values of ICH score in the prognosis of mortality within 30-days after the onset of NOAC-ICH or VKA-ICH. We analyzed data from 108 NOAC-ICH and 241 VKA-ICH patients (median age 76 years, 58% males, median NIHSS score 11 points, median ICH-score 2 points). ICH score of 4 points was uncovered to be the most favorable threshold for the prediction of 30-day mortality both after NOAC-ICH (sensitivity: 57.7%, specificity: 98.8%) or VKA-ICH (sensitivity: 42.1%, specificity: 92.6%). However, comparison of the areas under the curve (AUC) suggested a cumulatively higher (p = .001) predictive value of ICH-score in the prognostication of 30-day mortality after ICH related to the use of NOACs (AUC: 0.92, 95%CI: 0.86–0.98) compared to the ICH related to the use of VKAs (AUC: 0.77, 95%CI: 0.70–0.83). In conclusion, ICH score seems to have an adequate predictive utility in the prognostication of 30-day mortality following an ICH related to the use of oral anticoagulants, with better yield in ICH cases associated with the use of NOACs. | |
dc.language.iso | en | |
dc.publisher | ELSEVIER | |
dc.source | Elements | |
dc.subject | Science & Technology | |
dc.subject | Life Sciences & Biomedicine | |
dc.subject | Clinical Neurology | |
dc.subject | Neurosciences | |
dc.subject | Neurosciences & Neurology | |
dc.subject | OUTCOMES | |
dc.type | Article | |
dc.date.updated | 2021-06-29T05:37:09Z | |
dc.contributor.department | MEDICINE | |
dc.description.doi | 10.1016/j.jns.2019.116628 | |
dc.description.sourcetitle | JOURNAL OF THE NEUROLOGICAL SCIENCES | |
dc.description.volume | 409 | |
dc.published.state | Published | |
Appears in Collections: | Staff Publications Elements |
Show simple item record
Files in This Item:
File | Description | Size | Format | Access Settings | Version | |
---|---|---|---|---|---|---|
1-s2.0-S0022510X19323937.pdf | 438.8 kB | Adobe PDF | CLOSED | Published | ||
1-s2.0-S0022510X19323937.pdf | Published version | 438.8 kB | Adobe PDF | CLOSED | Published |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.