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https://doi.org/10.3174/ajnr.A2023
Title: | Treatment of intracranial aneurysms by functional reconstruction of the parent artery: The Budapest experience with the pipeline embolization device | Authors: | Szikora, I Berentei, Z Kulcsar, Z Marosfoi, M Vajda, Z.S Lee, W Berez, A Nelson, P.K |
Keywords: | acetylsalicylic acid clopidogrel heparin tirofiban cobalt nickel platinum aneurysm rupture artery reconstruction article clinical article coil embolization computed tomographic angiography device follow up headache hemiparesis human incidental finding intracranial aneurysm magnetic resonance angiography mortality neurologic disease ophthalmic artery pipeline embolization device posterior communicating artery recanalization retina blood vessel occlusion stent thrombosis subarachnoid hemorrhage thromboembolism treatment outcome artificial embolism brain angiography brain circulation Carotid Artery Diseases cavernous sinus clinical trial devices Hungary internal carotid artery intracranial aneurysm multicenter study procedures radiography stent surgical mesh Carotid Artery Diseases Carotid Artery, Internal Cavernous Sinus Cerebral Angiography Cerebrovascular Circulation Cobalt Embolization, Therapeutic Follow-Up Studies Humans Hungary Intracranial Aneurysm Nickel Ophthalmic Artery Platinum Stents Surgical Mesh Treatment Outcome |
Issue Date: | 2010 | Publisher: | American Society of Neuroradiology | Citation: | Szikora, I, Berentei, Z, Kulcsar, Z, Marosfoi, M, Vajda, Z.S, Lee, W, Berez, A, Nelson, P.K (2010). Treatment of intracranial aneurysms by functional reconstruction of the parent artery: The Budapest experience with the pipeline embolization device. American Journal of Neuroradiology 31 (6) : 1139-1147. ScholarBank@NUS Repository. https://doi.org/10.3174/ajnr.A2023 | Rights: | Attribution 4.0 International | Abstract: | BACKGROUND AND PURPOSE: Aneurysm treatment by intrasaccular packing has been associated with a relatively high rate of recurrence. The use of mesh tubes has recently gained traction as an alternative therapy. This article summarizes the midterm results of using an endoluminal sleeve, the PED, in the treatment of aneurysms. MATERIALS AND METHODS: A total of 19 wide-neck aneurysms were treated in 18 patients: 10 by implantation of PEDs alone and 9 by a combination of PED and coils. Angiographic and clinical results were recorded immediately and at 6 months following treatment. RESULTS: Immediate angiographic occlusion was achieved in 4 and flow reduction, in another 15 aneurysms. Angiography at 6 months demonstrated complete occlusion in 17 and partial filling in 1 of 18 patients. There was no difference between coil-packed and unpacked aneurysms. Of 28 side branches covered by ?1 device, the ophthalmic artery was absent immediately in 1 and at 6 months in another 2 cases. One patient experienced abrupt in-stent thrombosis resulting in a transient neurologic deficit, and 1 patient died due to rupture of a coexisting aneurysm. All giant aneurysms treated with PED alone were demonstrated by follow-up cross-sectional imaging to have involuted by 6 months. CONCLUSIONS: Treatment of large, wide-neck, or otherwise untreatable aneurysms with functional reconstruction of the parent artery may be achieved with relative safety using dedicated flow-modifying devices with or without adjunctive use of intrasaccular coil packing. | Source Title: | American Journal of Neuroradiology | URI: | https://scholarbank.nus.edu.sg/handle/10635/183918 | ISSN: | 0195-6108 | DOI: | 10.3174/ajnr.A2023 | Rights: | Attribution 4.0 International |
Appears in Collections: | Staff Publications Elements |
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